| Identification | More | [Name]
Quintozine | [CAS]
82-68-8 | [Synonyms]
1,2,3,4,5-PENTACHLORO-6-NITROBENZENE
BRASSICOL
BRASSICOL(R)
FOLOSAN
FOLOSAN(R)
KOBUTOL
'LGC' (1125)
PCNB
PCNB(R)
PENTACHLORONITROBENZENE
QUINTOZEN
QUINTOZENE
quintozine
TERRACLOR
TERRACLOR(R)
TRITISAN(R)
101brandpcnb75wettable
ai-23024
Avicol
avicol(pesticide) | [EINECS(EC#)]
201-435-0 | [Molecular Formula]
C6Cl5NO2 | [MDL Number]
MFCD00007065 | [Molecular Weight]
295.33 | [MOL File]
82-68-8.mol |
| Chemical Properties | Back Directory | [Appearance]
Quintozene is a colorless to cream-colored
crystalline material. Musty, mothball odor. Technical-grade
PCNB contains an average of 97.8% PCNB, 1.8% hexa-
chlorobenzene (HCB), 0.4% 2,3,4,5-tetrachloronitrobenzene
(TCNB), and less than 0.1% pentachlorobenzene. Musty
odor. | [Melting point ]
140-143 °C(lit.)
| [Boiling point ]
328°C | [density ]
1.718 | [vapor pressure ]
1.27 x l0-2Pa (25 °C) | [Fp ]
11 °C | [storage temp. ]
APPROX 4°C
| [solubility ]
toluene: soluble50mg/mL, clear, faintly to slightly yellow | [form ]
powder
| [color ]
yellow to tan
| [Stability:]
Stable. Incompatible with strong bases, strong oxidizing agents. | [Water Solubility ]
Insoluble | [Merck ]
8080 | [BRN ]
1914324 | [Contact allergens]
Pentachloronitrobenzene is a pesticide and a fungicide.
Sensitization can occur in farmers or in chemical plants. | [CAS DataBase Reference]
82-68-8(CAS DataBase Reference) | [IARC]
3 (Vol. 5, Sup 7) 1987 | [NIST Chemistry Reference]
Benzene, pentachloronitro-(82-68-8) | [EPA Substance Registry System]
82-68-8(EPA Substance) |
| Hazard Information | Back Directory | [Chemical Properties]
Light green powder | [Chemical Properties]
Quinalphos is an off-white powder. It is stable and incompatible with strong bases and
strong oxidizing agents. Quinalphos is uses as a fungicide and herbicide. | [Definition]
ChEBI: A C-nitro compound that is nitrobenzene in which every hydrogen has been replaced by a chlorine. A fungicide used on a variety of crops, including cotton, rice and seed grains, it is no longer approved for use within the European Union. | [Uses]
Fungicide for seed and soil treatment. | [General Description]
Crystalline pale yellow to white solid or powder with a musty moth ball odor. Insoluble in water and denser than water. Hence sinks in water. | [Reactivity Profile]
QUINTOZENE(82-68-8) is hydrolyzed by alkalis. Is incompatible with strong oxidizing agnets. Also incompatible with strong bases. Corrosive to unlined metal containers . | [Air & Water Reactions]
Insoluble in water. | [Health Hazard]
Exposures to quinalphos cause toxicity and adverse health effects. On contact with the
skin, quinalphos causes the effects of sensitization. | [Potential Exposure]
Those engaged in manufacture, formulation
and application of this soil fungicide and seed treatment
chemical. Peracetic acid is often used as a sterilizing
agent in the medical, food service and pharmaceutical industries
in combination hydrogen peroxide and acetic acid. | [Fire Hazard]
Flash point data for this chemical are not available; however, QUINTOZENE is probably combustible. | [First aid]
Move victim to fresh air. Call 911 or emergency
medical service. Give artificial respiration if victim is not
breathing. Do not use mouth-to-mouth method if victim
ingested or inhaled the substance; give artificial respiration
with the aid of a pocket mask equipped with a one-way
valve or other proper respiratory medical device.
Administer oxygen if breathing is difficult. Remove and
isolate contaminated clothing and shoes. In case of contact
with substance, immediately flush skin or eyes with running
water for at least 20 minutes. For minor skin contact,
avoid spreading material on unaffected skin. Keep victim
warm and quiet. Effects of exposure (inhalation, ingestion
or skin contact) to substance may be delayed. Ensure that
medical personnel are aware of the material(s) involved
and take precautions to protect themselves. Medical observation
is recommended for 2448 hours after breathing
overexposure, as pulmonary edema may be delayed.
As first aid for pulmonary edema, a doctor or authorized
paramedic may consider administering a drug or other
inhalation therapy. | [Shipping]
UN3077 Environmentally hazardous substances,
solid, n.o.s., Hazard class: 9; Labels: 9-Miscellaneous
hazardous material, Technical Name Required. UN2811 Toxic solids, organic, n.o.s., Hazard Class: 6.1; Labels:
6.1-Poisonous materials, Technical Name Required. | [Incompatibilities]
Incompatible with oxidizers (chlorates,
nitrates, peroxides, permanganates, perchlorates, chlorine,
bromine, fluorine, etc.); contact may cause fires or explo-
sions. Keep away from alkaline materials, strong bases,
strong acids, oxoacids, epoxides. Thermal decomposition
products may include nitrogen oxides and hydrogen chlo-
ride. Corrosive to unlined metal containers . | [Description]
Pentachloronitrobenzene (PCNB) is a pesticide and
fungicide. Sensitization can occur in farmers and in
those working in chemical plants. | [Waste Disposal]
Dispose of contents/container
to an approved waste disposal plant or consult with envi-
ronmental regulatory agencies for guidance on
acceptable disposal practices. Generators of waste contain-
ing this contaminant (≥100 kg/mo) must conform to EPA
regulations governing storage, transportation, treatment,
and waste disposal. In accordance with 40CFR165, follow
recommendations for the disposal. | [Agricultural Uses]
Soil fungicide, Nematicide, Seed treatment: Quintozene, the common name for PCNB or pentachlkoronitrobenzene, is an organochlorine fungicide used as a seed dressing or soil treatment to control a wide range of fungi species in such crops as potatoes, wheat, onions, lettuce, tomatoes, tulips, garlic, and others. Depending on the producer and the manufacturing procedure, PCNB impurities can include hexachlorobenzene, pentachlorobenzene, and tetrachloronitrobenzene. The fungicide is often used in combination with insecticides and fungicides including carbaryl, imazalil, tridimenol, etridiazole, and fuberidazole. It is available as a dustable or wettable powder, in granular form, emulsifiable concentrate, and seed treatment. Not approved for use in EU countries. Registered for use in the U.S. and Canada. There are more than 35 global suppliers. | [Trade name]
(EPA lists 290 active and canceled or transferred products) AVICOL (PESTICIDE)®; BOTRILEX®; BLOCKER 4F®; BOTRILEX®; BRASSICOL®; BRASSICOL EARTHCIDE®; BRASSICOL 75®; BRASSICOL SUPER®; CHINOZAN®; EARTHCIDE®; FARTOX®; FOLOSAN®; FOMAC 2®; FUNGICHLOR®; GC 3944-3-4®; KOBU®; KOBUTOL®; KODIAK A-T FUNGICIDE®; KP 2®; MARISAN FORTE®; MEFENOXAM®; PARFLO®; PENTAGEN®; PHOMASAN®; PKhNB®; RTU 1010®; SANICLOR 30®; TERRACHLOR®; TERRACLOR®; TERRACLOR 30G®; TERRA-COAT®; TERRAFUN®; TERRAZAN®; TILCAREX®; TRIPCNB®; TRIQUINTAM®; TRITISAN®; TUBERGRAN®; TURFCIDE®; VITAVAX® Quintozene | [Environmental Fate]
Biological. Pentachloronitrobenzene is rapidly degraded in flooded soils forming pentachloroaniline. When pentachloronitrobenzene was incubated in a submerged soil and
moist soil for 3 weeks, the percentages of the applied dosage remaining were <1 and 82%,
respectively. Chacko et al. (1966) reported microorganisms can convert pentachloronitrobenzene to pentachloroaniline and pentachlorothioanisole
Soil. The half-lives of pentachloronitrobenzene in a Columbia fine sandy loam, Sacramento clay and Staten peaty muck from California were 4.7, 7.6 and 9.7 months,
respectively. Degradation products were pentachloroaniline and pentachlorothioanis
When heated to decomposition (330°C), emits toxic fumes of nitrogen oxides and
chlorine (Sax and Lewis, 1987) | [Metabolic pathway]
Renner (1981) has reviewed the metabolism of quintozene. Fate in soil,
plants, several animal species and fish has been reported. The nitro group
provides a reactive centre, which allows rapid metabolism via three
primary routes: nitro reduction, glutathione-dependent denitration and
dechlorination. Thus a very complex array of metabolites is formed.
Quintozene is relatively persistent in soil in comparison with plants
and animals. It was one of the compounds which stimulated the study
and understanding of the catabolism of glutathione conjugates in
plants and animals and this was properly elucidated for the first
time using such compounds. Nitro reduction and nitro displacement is
quite rapid and therefore quintozene is much less persistent than is
hexachlorobenzene. The latter shares one of the primary metabolites
[ S-(pentachlorophenyl)glutathione] with quintozene and many of the
sulfur-containing metabolites are common to both compounds. | [Purification Methods]
Crystallise it from EtOH. [Beilstein 5 H 247, 5 II 188, 5 III 618.] | [Degradation]
Quintozene is a stable compound. It is stable in acidic media but is
hydrolysed in base (PM). The nitro group is liable to displacement by
thiolysis. |
| Safety Data | Back Directory | [Hazard Codes ]
Xi,N,T,F,Xn | [Risk Statements ]
R43:May cause sensitization by skin contact.
R50/53:Very Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment .
R39/23/24/25:Toxic: danger of very serious irreversible effects through inhalation, in contact with skin and if swallowed .
R23/24/25:Toxic by inhalation, in contact with skin and if swallowed .
R11:Highly Flammable.
R40:Limited evidence of a carcinogenic effect. | [Safety Statements ]
S13:Keep away from food, drink and animal feeding stuffs .
S24:Avoid contact with skin .
S37:Wear suitable gloves .
S60:This material and/or its container must be disposed of as hazardous waste .
S61:Avoid release to the environment. Refer to special instructions safety data sheet .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S36/37:Wear suitable protective clothing and gloves . | [RIDADR ]
UN 3077 9/PG 3
| [WGK Germany ]
2
| [RTECS ]
DA6650000
| [HazardClass ]
9 | [PackingGroup ]
III | [HS Code ]
29049090 | [Safety Profile]
Moderately toxic by ingestion. An experimental teratogen. Questionable carcinogen with experimental carcinogenic data. Mutation data reported. Used as a fungcide. Dangerous; when heated to decomposition it emits highly toxic fumes of NO, and Cl-. See also NITRO COMPOUNDS OF AROMATIC HYDROCARBONS | [Hazardous Substances Data]
82-68-8(Hazardous Substances Data) | [Toxicity]
LD50 in male, female rats (g/kg): 1.71 ±0.20, 1.65 ±0.17 by gavage (Finnegan) |
|