| Identification | Back Directory | [Name]
Tifenamil | [CAS]
82-99-5 | [Synonyms]
thiphenamil
Diphenylthioacetic acid S-[2-(diethylamino)ethyl]
Diphenylthioacetic acid S-[2-(diethylamino)ethyl] ester
Benzeneethanethioic acid, α-phenyl-, S-[2-(diethylamino)ethyl] ester | [Molecular Formula]
C20H25NOS | [MDL Number]
MFCD00396147 | [MOL File]
82-99-5.mol | [Molecular Weight]
327.49 |
| Hazard Information | Back Directory | [Originator]
Trocinate,Poythress,US,1950 | [Definition]
ChEBI: Tifenamil is a diarylmethane. | [Manufacturing Process]
The following procedure is described in US Patent 2,510,773: To an ice-cold
solution of 13.3 grams of 2-diethylaminoethanethiol in 100 cc of dry benzene
is slowly added a solution of 23.05 grams of diphenylacetyl chloride in 200 cc
of dry benzene. The mixture is stirred 2 hours, then heated to dissolve the
fine white solid that is formed. Upon cooling 31.3 grams of 2-
diethylaminoethyl diphenylthiolacetate hydrochloride precipitates. It
recrystallizes from a mixture of benzene and petroleum ether (BP 60° to
70°C) as rosettes of tiny needles and melts at 129° to 130°C. From a mixture
of absolute ethanol and ethyl acetate it recrystallizes as large, almost
transparent prisms. | [Brand name]
Tifenamil is INN. | [Therapeutic Function]
Spasmolytic |
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