| Identification | Back Directory | [Name]
Card-20(22)-enolide, 3-[(O-β-D-glucopyranosyl-(1→6)-O-β-D-glucopyranosyl-(1→4)-2-O-acetyl-6-deoxy-3-O-methyl-α-L-glucopyranosyl)oxy]-14-hydroxy-, (3β,5β)- | [CAS]
82145-55-9 | [Synonyms]
2'- O -Acetylthevetin B
Card-20(22)-enolide, 3-[(O-β-D-glucopyranosyl-(1→6)-O-β-D-glucopyranosyl-(1→4)-2-O-acetyl-6-deoxy-3-O-methyl-α-L-glucopyranosyl)oxy]-14-hydroxy-, (3β,5β)- | [Molecular Formula]
C44H68O19 | [MOL File]
82145-55-9.mol | [Molecular Weight]
901.01 |
| Hazard Information | Back Directory | [Uses]
2'-epi-2'-O-Acetylthevetin B (GHSC-74) is a cardiac glycoside that can be isolated from the seeds of Cerbera manghas L. 2'-epi-2'-O-Acetylthevetin B inhibits cell viability, induces apoptosis and loss of mitochondrial membrane potential in HepG2 cells[1]. | [References]
[1] Feng B, et al. 2'-Epi-2'-O-acetylthevetin B induces apoptosis partly via Ca(2+)-mediated mitochondrial pathway in human hepatocellular carcinoma HepG2 cells. Cell Biol Int. 2009 Sep;33(9):918-25. DOI:10.1016/j.cellbi.2009.06.013 |
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