| Identification | Back Directory | [Name]
RA 263 | [CAS]
82205-95-6 | [Synonyms]
RA 263
Nsc342714
1-(2,3-Dideoxy-α-D-erythro-hexa-2-enopyranosyl)-2-nitro-1H-imidazole | [Molecular Formula]
C9H11N3O5 | [MDL Number]
MFCD01721597 | [MOL File]
82205-95-6.mol | [Molecular Weight]
241.202 |
| Hazard Information | Back Directory | [Description]
RA 263 is a nucleoside. | [Uses]
RA-263, a 2-nitroimidazole nucleoside, is an effective radiosensitizer[1][2]. | [in vivo]
RA-263 is eliminated from plasma by a rapid alpha phase and a slower beta phase with T1/2 of 36 and 72 min, respectively[2]. | [References]
[1] K C Agrawal, et al. Radiosensitization, pharmacokinetics, and toxicity of a 2-nitroimidazole nucleoside (RA-263). Radiat Res. 1986 Feb;105(2):227-39. PMID:3754053
[2] K C Agrawal, et al. A new potent radiosensitizer: 1-(2',3'-dideoxy-alpha-D-erythro-hex-2'-enopyranosyl)-2-nitroimidazole (RA-263). Int J Radiat Oncol Biol Phys. 1982 Mar-Apr;8(3-4):403-7. DOI:10.1016/0360-3016(82)90648-4 |
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