ChemicalBook--->CAS DataBase List--->823178-43-4

823178-43-4

823178-43-4 Structure

823178-43-4 Structure
IdentificationBack Directory
[Name]

ANAGRELIDE HCL MONOHYDRATE
[CAS]

823178-43-4
[Synonyms]

ANAGRELIDE HCL MONOHYDRATE
Anagrelide Hydrochloride (100 mg)
Anagrelide Hydrochloride (1034738)
[Molecular Formula]

C10H7Cl2N3O.ClH.H2O
[MDL Number]

MFCD09839188
[MOL File]

823178-43-4.mol
[Molecular Weight]

310.564
Chemical PropertiesBack Directory
[storage temp. ]

2-8°C
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302
[Precautionary statements ]

P264-P270-P301+P312-P330-P501
[HS Code ]

2933595960
Hazard InformationBack Directory
[Uses]

Anagrelide Hydrochloride Monohydrate is an anhydrous salt of Anagrelide. Anagrelide is a platelet-??lowering drug that inhibits bone marrow megakaryocytopoiesis.
[in vivo]

Anagrelide (5 mg/kg/bid; for 10 days) hydrochloride monohydrate inhibits or reduces tumor growth in GIST2B, GIST9, GIST882 model models[3].

Animal Model:Adult female athymic mice bearing GIST2B, GIST3, GIST9, GIST882 model[3]
Dosage:5 mg/kg
Administration:Twice daily; for 10 days
Result:Inhibited or reduced tumor growth in three (GIST2B, GIST9, GIST882) of these four models.
[IC 50]

PDE3
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