| Identification | Back Directory | [Name]
4H-1-Benzopyran-4-one, 2-(2,6-dihydroxyphenyl)-5,7-dihydroxy- | [CAS]
82475-00-1 | [Synonyms]
Luteolin Impurity 2
2',5,6',7-Tetrahydroxyflavone
2,5,6,7-Tetrahydroxyflavone/ 5,7,2,6-Tetrahydroxyflavone
4H-1-Benzopyran-4-one, 2-(2,6-dihydroxyphenyl)-5,7-dihydroxy- | [Molecular Formula]
C15H10O6 | [MOL File]
82475-00-1.mol | [Molecular Weight]
286.24 |
| Hazard Information | Back Directory | [Uses]
5,7,2',6'-Tetrahydroxyflavone is a natural flavonoid that inhibits hepatic testosterone 6β-hydroxylation (CYP3A4) activity with an IC50 of 7.8 μM[1]. | [IC 50]
CYP3A4: 7.8 μM (IC50) | [References]
[1] Ji-Yeon Kim, et al. Effects of flavonoids isolated from Scutellariae radix on cytochrome P-450 activities in human liver microsomes. J Toxicol Environ Health A. 2002 Mar;65(5-6):373-81. DOI:10.1080/15287390252808046 |
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