| Identification | Back Directory | [Name]
JWH-182 | [CAS]
824960-02-3 | [Synonyms]
JWH-182
1-PENTYL-3-(4-PROPYL-1-NAPHTHOYL)INDOLE
(1-Pentyl-1H-indol-3-yl)(4-propylnaphthalen-1-yl)methanone
Methanone, (1-pentyl-1H-indol-3-yl)(4-propyl-1-naphthalenyl)- | [Molecular Formula]
C27H29NO | [MOL File]
824960-02-3.mol | [Molecular Weight]
383.53 |
| Chemical Properties | Back Directory | [Boiling point ]
568.3±33.0 °C(Predicted) | [density ]
1.06±0.1 g/cm3(Predicted) | [solubility ]
DMF: 50 mg/ml; DMSO: 20 mg/ml; Ethanol: 0.5 mg/ml | [form ]
A crystalline solid |
| Hazard Information | Back Directory | [Description]
JWH 182 is a potent synthetic cannabinoid (CB), activating the central CB1 receptor with a Ki value of 0.65 nM and the peripheral CB2 receptor with a Ki value of 1.1 nM. Its effects in cells and animals are unknown. | [Uses]
JWH 182 is a potent synthetic cannabinoid (CB), activating the central CB1 receptor with a Ki value of 0.65 nM and the peripheral CB2 receptor with a Ki value of 1.1 nM. Its effects in cells and animals are unknown.[Cayman Chemical] | [Uses]
JWH 182, is a potent synthetic cannabinoid (CB), activating the central CB1 receptor with a Ki value of 0.65 nM and the peripheral CB2 receptor with a Ki value of 1.1 nM. Synthetic Cannabinoids | [References]
[1] JOHN W. HUFFMAN . Structure–activity relationships for 1-alkyl-3-(1-naphthoyl)indoles at the cannabinoid CB1 and CB2 receptors: steric and electronic effects of naphthoyl substituents. New highly selective CB2 receptor agonists[J]. Bioorganic & Medicinal Chemistry, 2005, 13 1: Pages 89-112. DOI: 10.1016/j.bmc.2004.09.050 |
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