| Hazard Information | Back Directory | [Description]
1,2-Dipalmitoyl-d6-rac-glycero-3-PC is intended for use as an internal standard for the quantification of 1,2-dipalmitoyl-rac-glycero-3-PC by GC- or LC-MS. 1,2-Dipalmitoyl-rac-glycero-3-PC is a phospholipid that contains palmitic acid at the sn-1 and sn-2 positions. It has been used as a component of liposomes, monolayers, and bilayers to study the influence of chirality on membrane dynamics.1,2,3,4 1,2-dipalmitoyl-rac-glycero-3-PC has been used to study electric field-induced orientation of phospholipid head groups and dynamics of liposomal phase transitions.2,3 | [Uses]
(Rac)-DPPC-d6 is a deuterated labeled DPPC[1]. DPPC (129Y83) is a phosphoglyceride that can be used to prepare lipid monolayers, bilayers, and liposomes. DPPC is the main lipid component of pulmonary surfactant. Dppc-liposome can be effectively used as a delivery vector to induce an immune response against GSL antigen in mice[2][3][4][5][6]. | [References]
1. Vollhardt, D., Nandi, N., and Banki, S.D. Nanoaggregate shapes at the air/water interface Phys. Chem. Chem. Phys. 13(11),4812-4829(2011).
2. Mishima, K., Tanaka, S., and Ogihara, T. Electric field-induced orientation of L- and DL-phosphatidylcholine bilayers Biochim. Biophys. Acta 1565(1),107-111(2002).
3. Boyanov, A.I., Tenchov, B.G., Koynova, R.D., et al. Absence of subtransition in racemic dipalmitoylphosphatidylcholine vesicles Biochim. Biophys. Acta 732,711-713(1983).
4. Moy, V.T., Keller, D.J., Gaub, H.E., et al. Long-range molecular orientational order in monolayer solid domains of phospholipid J. Phys. Chem. 90(14),3198-3202(1986). |
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