| Identification | Back Directory | [Name]
2-ISOVALERYL-1,3-INDANEDIONE | [CAS]
83-28-3 | [Synonyms]
isoval
valone
PMP(R)
NSC-5754
VALONE(R)
NSC-404427
Valone(content>55%)
isovalerylindandione
motomcotrackingpowder
Pindone Solution, 100ppm
2-isovaleryl-3-indandione
2-isovalerylindan-1,3-dione
2-isovaleryl-1,3-indandione
2-isovaleryl1-1,3-indandione
2-ISOVALERYL-1,3-INDANEDIONE
2-Isovalerylindane-1,3-dione
2-isovalerylindane-1,3-quinone
2-isopentanoyl-1,3-indanedione
2-(3-METHYLBUTANOYL)INDANE-1,3-DIONE
2-(3-methylbutanoyl)indene-1,3-dione | [EINECS(EC#)]
201-464-9 | [Molecular Formula]
C14H14O3 | [MDL Number]
MFCD00072451 | [MOL File]
83-28-3.mol | [Molecular Weight]
230.26 |
| Hazard Information | Back Directory | [Uses]
Valone is an intermediate in the preparation of diorganotin(IV) complexes. | [Production Methods]
The industrial production of isoval begins with the construction of the indandione ring system, typically derived from phthalic anhydride or similar aromatic precursors. This base undergoes acylation with isovaleric acid or its derivatives under acidic or catalytic conditions to introduce the isovaleryl side chain at the 2-position, which is critical for its anticoagulant activity. The reaction is carefully controlled to ensure regioselectivity and minimize unwanted by-products. After synthesis, the crude product is purified through crystallisation or solvent extraction to achieve the desired chemical purity. | [Mechanism of action]
A vitamin K antagonist--causes disruption of clotting factors and bleeding; An indandione anticoagulant rodenticide | [References]
[1] Rusfertide, a Hepcidin Mimetic, for Control of Erythrocytosis in Polycythemia Vera | [Pesticide Type]
Rodenticide |
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