| Identification | Back Directory | [Name]
STIGMASTANOL | [CAS]
83-45-4 | [Synonyms]
Nsc49081
Aids113421
FUCOSTANOL
SIGMASTANOL
SPINASTANOL
Aids-113421
-SITOSTANOL
STIGMASTANOL
BETA-SITOSTANOL
STIGMASTANOL(SG)
BETA-SISTOSTANOL
DIHYDROSITOSTERIN
24-ETHYLCHOLESTANOL
STIGMASTAN-3BETA-OL
-SITOSTANOL;SITOSTANOL
DIHYDRO-BETA-SITOSTEROL
24-ALPHA-ETHYLCHOLESTANOL
BETA-SITOSTEROL, DIHYDRO-
5,6-DIHYDRO-BETA-SITOSTEROL
24-ETHYL-5A-CHOLESTAN-3BETA-OL
(3beta,5alpha)-stigmastan-3-ol
Stigmastan-3-ol, (3.beta.,5.alpha.)-
24ALPHA-ETHYL-5ALPHA-CHOLESTAN-3BETA-OL
5-ALPHA-CHOLESTAN-24-BETA-ETHYL-3-BETA-OL
24-Ethyl-5α(H)-cholestan-3-ol (β-Sitostanol)
(3S,10S,13R,17R)-17-((1R,4R)-4-Ethyl-1,5-dimethyl-hexyl)-10,13-dimethyl-hexadecahydro-cyclopenta[A]phenanthren-3-ol
17-(5-ethyl-6-methyl-heptan-2-yl)-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol | [EINECS(EC#)]
201-479-0 | [Molecular Formula]
C29H52O | [MDL Number]
MFCD00021167 | [MOL File]
83-45-4.mol | [Molecular Weight]
416.72 |
| Chemical Properties | Back Directory | [Melting point ]
144°C | [Boiling point ]
474.98°C (rough estimate) | [density ]
0.9444 (rough estimate) | [refractive index ]
1.5000 (estimate) | [storage temp. ]
Store at -20°C | [solubility ]
Chloroform: Slightly Soluble | [form ]
A solid | [pka]
15.14±0.70(Predicted) | [color ]
White to off-white | [InChIKey]
LGJMUZUPVCAVPU-HRJGVYIJSA-N | [SMILES]
O[C@@H]1C[C@H]2[C@@]([C@@H]3[C@H]([C@H]4[C@@]([C@H](CC4)[C@@H](CC[C@H](C(C)C)CC)C)(CC3)C)CC2)(CC1)C |
| Hazard Information | Back Directory | [Uses]
Stigmastanol is used in food product formulations for prevention and treatment of hypercholesterolemia, hypertension and inflammation disorders in humans | [Definition]
ChEBI: A 3-hydroxy steroid that is 5alpha-stigmastane which is substituted at the 3beta position by a hydroxy group. | [Biological Activity]
Plant stanols are structurally similar to cholesterolhence it reduces the plasma level of LDL cholesterol. Sitostanol is known to possess hypolipidemic and antiatherogenic effects.''Sitostanol decreases cholesterol absorption. Its ratio with cholesterol is implicated in non-alcoholic fatty liver disease (NAFLD). The ratio also correlates with liver steatosis and inflammation. Sitostanol induces interferon γ production and T-helper response in peripheral blood mononuclear cells (PBMC) in asthma patients. It is a hypocholestremic agent as it decreases the micellar solubility and absorption of cholesterol.''Sitostanol lowers the intestinal absorption of cholesterol and serum cholesterol. | [IC 50]
Human Endogenous Metabolite |
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| Company Name: |
Energy Chemical
|
| Telephone: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
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