| Identification | Back Directory | [Name]
RP-TTP-ALPHA-S/RP-DTTP-ALPHA-S SODIUM SALT | [CAS]
83199-32-0 | [Synonyms]
Sp-TTP-α-S dTTPαS (Sp isomer) 100mM Sodium Solution SP-TTP-ALPHA-S/SP-DTTP-ALPHA-S SODIUM SALT RP-TTP-ALPHA-S/RP-DTTP-ALPHA-S SODIUM SALT thymidine-5’-o-(1-thiotriphosphate),sp-isomer(sp-ttp-alpha-s),sodiumsalt Thymidine, 5-P-ester with thiotriphosphoric acid ((HO)2P(O)OP(O)(OH)OP(S)(OH)2), (S)- THYMIDINE-5'-O-(1-THIOTRIPHOSPHATE), RP-ISOMER/2'-DEOXYTHYMIDINE-5'-O-(1-THIOTRIPHOSPHATE), RP-ISOMER SODIUM SALT THYMIDINE-5'-O-(1-THIOTRIPHOSPHATE), SP-ISOMER/2'-DEOXYTHYMIDINE-5'-O-(1-THIOTRIPHOSPHATE), SP-ISOMER SODIUM SALT | [Molecular Formula]
C10H13N2Na4O13P3S | [MDL Number]
MFCD04118069 | [MOL File]
83199-32-0.mol | [Molecular Weight]
586.16 |
| Hazard Information | Back Directory | [Uses]
Sp-TTPαS is a competitivesterile alpha motif and HD domain containing protein 1 (SAMHD1) catalysis inhibitor. Sp-TTPαS competitively inhibits TTP hydrolysis with a Ki value of 46 μM[1]. | [References]
[1] Morris ER, et al. Probing the Catalytic Mechanism and Inhibition of SAMHD1 Using the Differential Properties of Rp- and Sp-dNTPαS Diastereomers. Biochemistry. 2021 Jun 1;60(21):1682-1698. DOI:10.1021/acs.biochem.0c00944 |
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BOC Sciences
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16314854226 |
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Enzo Biochem Inc
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Enzo Biochem Inc. 13797054060 |
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www.enzo.com |
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