ChemicalBook--->CAS DataBase List--->832107-31-0

832107-31-0

832107-31-0 Structure

832107-31-0 Structure
IdentificationBack Directory
[Name]

B-Raf IN 15
[CAS]

832107-31-0
[Synonyms]

B-Raf IN 15
[Molecular Formula]

C19H15N3OS
[MOL File]

832107-31-0.mol
[Molecular Weight]

333.41
Chemical PropertiesBack Directory
[Boiling point ]

569.100±45.00 °C(Press: 760.00 Torr)(predicted)
[density ]

1.378±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
[form ]

Solid
[pka]

4.318±0.50(predicted)
[color ]

Off-white to light yellow
Hazard InformationBack Directory
[Uses]

B-Raf IN 15 (Compound 7) is a BRAF inhibitor. B-Raf IN 15 inhibits BRAF WT and BRAF V600E with IC50s of 2.0 and 0.8 μM. B-Raf IN 15 can be used for the research of cancer[1].
[References]

[1] Qin J, et al. Identification of a novel family of BRAF(V600E) inhibitors. J Med Chem. 2012 Jun 14;55(11):5220-30. DOI:10.1021/jm3004416
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