| Identification | Back Directory | [Name]
4-METHOXYDIPHENYLMETHANE | [CAS]
834-14-0 | [Synonyms]
4-MDM
p-Benzylanisole
4-Benzylanisole
Anisole, p-benzyl-
4-MDM >=98% (HPLC)
p-Anisylphenylmethane
4-METHOXYDIPHENYLMETHANE
p-Methoxydiphenylmethane
1-Benzyl-4-methoxybenzene
4-Methoxyphenylphenylmethane
p-Methoxyphenylphenylmethane
4-METHOXYDIPHENYLMETHANE 98%
(4-Methoxyphenyl)phenylmethane
1-methoxy-4-(phenylmethyl)benzene
Benzene, 1-methoxy-4-(phenylmethyl)-
4-(4-Methoxy-2,5-dimethylphenyl)-1,3-thiazol-2-ami | [Molecular Formula]
C14H14O | [MDL Number]
MFCD00094072 | [MOL File]
834-14-0.mol | [Molecular Weight]
198.26 |
| Hazard Information | Back Directory | [Uses]
4-MDM (4-Methoxydiphenylmethane) is an orally active anti-inflammatory compound that selectively enhances the Leukotriene A4 Hydrolase (LTA4H) aminopeptidase enzyme activity. 4-MDM reduces the neutrophil recruitment in the lung by enhancing the degradation of proline-glycine-proline by LTA4H, thereby reducing inflammation, and does not affect the epoxy-hydrolase activity of LTA4H. 4-MDM can be used for research on lung diseases[1]. | [Synthesis Reference(s)]
Tetrahedron Letters, 28, p. 2387, 1987 DOI: 10.1016/S0040-4039(00)96131-8 | [References]
[1] Farhan N, et al. Ultrapressure liquid chromatography-tandem mass spectrometry assay using atmospheric pressure photoionization (UPLC-APPI-MS/MS) for quantification of 4-methoxydiphenylmethane in pharmacokinetic evaluation. J Pharm Biomed Anal. 2016 Sep 5;128:46-52. DOI:10.1016/j.jpba.2016.05.014 |
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