| Identification | Back Directory | [Name]
ATPA | [CAS]
83654-14-2 | [Synonyms]
ATPA
(R,S)-ATPA
ATPA solid
ATPA ((RS)-2-AMINO-3-(3-HYDROXY-5-TERT-B
(RS)-A-AMINO-3-HYDROXY-5-TERT-BUTYL-4-ISOXAZOLEPROPIONIC ACID
(R,S)-ALPHA-AMINO-3-HYDROXY-5-T-BUTYL-4-ISOXAZOLEPROPIONIC ACID
(RS)-ALPHA-AMINO-3-HYDROXY-5-TERT-BUTYL-4-ISOXAZOLEPROPIONIC ACID
(RS)-2-AMINO-3-(3-HYDROXY-5-TERT-BUTYLISOXAZOL-4-YL)PROPANOIC ACID
(RS)-2-Amino-3-(3-hydroxy-5-tert-butyliosxazol-4-yl)propanoic acid
α-Amino-5-(1,1-dimethylethyl)-2,3-dihydro-3-oxo-4-isoxazolepropanoic acid | [Molecular Formula]
C10H16N2O4 | [MDL Number]
MFCD01860864 | [MOL File]
83654-14-2.mol | [Molecular Weight]
228.25 |
| Chemical Properties | Back Directory | [Melting point ]
>231°C (dec.) | [storage temp. ]
Refrigerator | [solubility ]
DMSO: 10 mg/mL | [form ]
solid | [color ]
white | [InChI]
1S/C10H16N2O4/c1-10(2,3)7-5(8(13)12-16-7)4-6(11)9(14)15/h6H,4,11H2,1-3H3,(H,12,13)(H,14,15) | [InChIKey]
PIXJURSCCVBKRF-UHFFFAOYSA-N | [SMILES]
CC(C)(C)c1onc(O)c1CC(N)C(O)=O |
| Hazard Information | Back Directory | [Uses]
(R,S)-ATPA is a selective and potent GluR5 kainate receptor agonist (1,2). It inhibits GluK2 kainate receptor-JNK3 protein pathway by activating GABA type A receptor in rat after cerebral ischemia-reperfusion injury (3). (R,S)-ATPA is a neuroprotective agent. | [Biological Activity]
Selective kainate receptor agonist. |
|
| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
| Company Name: |
Merck KGaA
|
| Tel: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
|