| Hazard Information | Back Directory | [Uses]
Cevoglitazar (LBM-642) is an orally active and highly potent PPARα and PPARγ dual agonist. Cevoglitazar can reduce food intake, body weight, and fasting plasma insulin in obese mice and cynomolgus monkeys. Cevoglitazar has the potential for diabetes and obesity-related disorders research[1]. | [IC 50]
PPARα; PPARγ | [References]
[1] Hong Chen, et al. Cevoglitazar, a novel peroxisome proliferator-activated receptor-alpha/gamma dual agonist, potently reduces food intake and body weight in obese mice and cynomolgus monkeys. Endocrinology. 2010 Jul;151(7):3115-24. DOI:10.1210/en.2009-1366 |
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