| Identification | Back Directory | [Name]
Xanthoxyletin | [CAS]
84-99-1 | [Synonyms]
NSC 35542
Xanthoxyloin
Xanthoxyletin
Xanthoxylin N
5-methoxy-8,8-dimethylpyrano[3,2-g]chromen-2-one
5-methoxy-2,2-dimethylpyrano[3,2-g]chromen-8-one
5-methoxy-8,8-dimethyl-pyrano[3,2-g]chromen-2-one
5-Methoxy-8,8-dimethyl-2H,8H-benzo[1,2-b:5,4-b']dipyran-2-one
2H,8H-Benzo[1,2-b:5,4-b']dipyran-2-one, 5-methoxy-8,8-dimethyl- | [Molecular Formula]
C13H12O2Sn | [MDL Number]
MFCD09838087 | [MOL File]
84-99-1.mol | [Molecular Weight]
318.943 |
| Chemical Properties | Back Directory | [Melting point ]
134-135℃ (ethanol ) | [Boiling point ]
321.52°C (rough estimate) | [density ]
1.1178 (rough estimate) | [refractive index ]
1.4300 (estimate) | [LogP]
3.640 (est) |
| Hazard Information | Back Directory | [Uses]
Xanthoxyletin is a coumarin that can be isolated from Genus Zanthoxylum and Clausena. Xanthoxyletin has antioxidant and anti-inflammatory activities. Xanthoxyletin shows cytotoxic effects to cancer cells, and induces apoptosis and necrosis. Xanthoxyletin can be used for the research of cancer and inflammation[1][2]. | [Definition]
ChEBI: A natural product found in Clausena harmandiana. | [References]
[1] Sanna MD, et al. Histamine H4 receptor stimulation in the locus coeruleus attenuates neuropathic pain by promoting the coeruleospinal noradrenergic inhibitory pathway. Eur J Pharmacol. 2020 Feb 5;868:172859. DOI:10.1016/j.ejphar.2019.172859
[2] Jantamat P, et al. Cytotoxicity and Apoptosis Induction of Coumarins and Carbazole Alkaloids from Clausena harmandiana. Molecules. 2019 Sep 18;24(18):3385. |
|
| Company Name: |
BioBioPha Co., Ltd.
|
| Tel: |
0871-65217109 13211707573; |
| Website: |
http://www.biobiopha.com |
| Company Name: |
BOC Sciences
|
| Tel: |
|
| Website: |
https://www.bocsci.com |
|