| Identification | Back Directory | [Name]
[1,2,4]Triazolo[1,5-c]pyriMidine, 7-[[2-(3-fluoro-2-pyridinyl)-1H-iMidazol-1-yl]Methyl]-2-Methyl-8-propyl- | [CAS]
840486-93-3 | [Synonyms]
NG 2-73
Adipiplon
[1,2,4]Triazolo[1,5-c]pyriMidine, 7-[[2-(3-fluoro-2-pyridinyl)-1H-iMidazol-1-yl]Methyl]-2-Methyl-8-propyl- | [Molecular Formula]
C18H18FN7 | [MDL Number]
MFCD19443700 | [MOL File]
840486-93-3.mol | [Molecular Weight]
351.38 |
| Hazard Information | Back Directory | [Uses]
Adipiplon (NG2-73) is a selective GABAA receptor positive allosteric modulator. Adipiplon is particularly useful in the research of a variety of central nervous system (CNS) disorders. | [References]
[1] Vinkers CH, Olivier B, Hanania T, et al. Discriminative stimulus properties of GABAA receptor positive allosteric modulators TPA023, ocinaplon and NG2-73 in rats trained to discriminate chlordiazepoxide or zolpidem. Eur J Pharmacol. 2011;668(1-2):190-193. DOI:10.1016/j.ejphar.2011.06.054
[2] Xie, Linghong; Han, Bingsong; Xu, Yuelian. et al. Preparation of imidazo-pyrimidines and triazolo-pyrimidines as benzodiazepine receptor ligands for the treatment of central nervous system diseases. WO2005012306A2. |
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