| Identification | Back Directory | [Name]
2-(5-methyl-1H-imidazol-4-yl)ethan-1-amine hydrochloride | [CAS]
84103-51-5 | [Synonyms]
4-Methylhistamine hydrochloride, 10 mM in DMSO 2-(5-methyl-1H-imidazol-4-yl)ethan-1-amine hydrochloride 2(5methyl1Himidazol4yl)ethan1amine hydrochloride,2 (5 methyl 1H imidazol 4 yl)ethan 1 amine hydrochloride | [Molecular Formula]
C6H12ClN3 | [MDL Number]
MFCD20233622 | [MOL File]
84103-51-5.mol | [Molecular Weight]
161.63 |
| Hazard Information | Back Directory | [Uses]
4-Methylhistamine (hydrochloride) is a potent, high affinity H4 receptor agonist Ki of 7 nM. 4-Methylhistamine (hydrochloride) displays more than 100-fold selectivity over other human histamine receptor subtypes[1]. | [References]
[1] Lim HD, et.al. Evaluation of histamine H1-, H2-, and H3-receptor ligands at the human histamine H4 receptor: identification of 4-methylhistamine as the first potent and selective H4 receptor agonist. J Pharmacol Exp Ther. 2005 Sep;314(3):1310-21. DOI:10.1124/jpet.105.087965 |
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