| Identification | Back Directory | [Name]
Zarilamid | [CAS]
84527-51-5 | [Synonyms]
Zarilamide
Benzamide, 4-chloro-N-(cyanoethoxymethyl)- | [Molecular Formula]
C11H11ClN2O2 | [MDL Number]
MFCD02101178 | [MOL File]
84527-51-5.mol | [Molecular Weight]
238.673 |
| Hazard Information | Back Directory | [Uses]
Zarilamid is a fungicide which is active against a broad spectrum of Oomycete fungi. Zarilamid inhibits nuclear division in germinating zoospore cysts of Phytophthora capsici. Zarilamide inhibits growth of tobacco roots and causes swelling of the root tips, destructs microtubule cytoskeleton and inhibits mitosis[1]. | [Production Methods]
The commercial production of zarilamid involves the synthesis of a chlorinated aromatic amide structure, specifically 4-chloro-N-(cyanoethoxymethyl)benzamide. The process begins with chlorination of a benzene ring followed by acylation and amidation steps to introduce the cyanoethoxymethyl side chain. | [Mechanism of action]
Anti-microtubular fungicide. | [References]
[1] David H. Young, et al. Effects of zarilamide on microtubules and nuclear division in Phytophthora capsici and tobacco suspension-cultured cells. Pesticide Biochemistry and Physiology. Volume 40, Issue 2, June 1991, Pages 149-161 | [Pesticide Type]
Fungicide |
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