| Identification | Back Directory | [Name]
quinocarcin | [CAS]
84573-33-1 | [Synonyms]
quinocarcin
Quinocarmycin
(-)-Quinocarcin
(2aR)-11-Methoxy-12-methyl-3β,6β-epimino-2aβ,3,4,5,6,6aβ,7,11bβ-octahydro-2-oxa-11c-aza-1H-naphtho[1,2,3-cd]azulene-5β-carboxylic acid | [Molecular Formula]
C20H26N2O4 | [MOL File]
84573-33-1.mol | [Molecular Weight]
358.435 |
| Hazard Information | Back Directory | [Uses]
(-)-Quinocarcin are potent antitumor antibiotics that plays a key role in the construction of tetracyclic THIQ-pyrrolidine core scaffold. | [in vivo]
Quinocarcin (40 mg/kg, i.p.) shows antitumor activity in mice[3]. | Animal Model: | Mice (SK-MEL-2 tumors) [3] | | Dosage: | 40 mg/kg | | Administration: | I.p.; on days 14, 21, and 28 | | Result: | Inhibited tumor growth by 89%. |
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