ChemicalBook--->CAS DataBase List--->845861-49-6

845861-49-6

845861-49-6 Structure

845861-49-6 Structure
IdentificationBack Directory
[Name]

2-METHYL-5-HYDROXYTRYPTAMINE HYDROCHLORIDE
[CAS]

845861-49-6
[Synonyms]

2-METHYLSEROTONIN HCL
2-Methyl-5-HT hydrochloride
2-METHYL-5-HYDROXYTRYPTAMINE HYDROCHLORIDE
[Molecular Formula]

C11H15ClN2O
[MDL Number]

MFCD02677991
[MOL File]

845861-49-6.mol
[Molecular Weight]

226.7
Chemical PropertiesBack Directory
[Melting point ]

225.5-227.0 °C
[storage temp. ]

Store at RT
[form ]

Powder
[Water Solubility ]

Soluble to 100 mM in water
Safety DataBack Directory
[Symbol(GHS) ]


GHS05
[Signal word ]

Danger
[Hazard statements ]

H318
[Precautionary statements ]

P280-P305+P351+P338-P310
Hazard InformationBack Directory
[Uses]

2-Methyl-5-hydroxytryptamine Hydrochloride is a 5-HT3 agonist and potent 5-HT6 ligand and affects the gut functions including secretion, muscle contraction and enteric nervous activity.
[in vivo]

2-Methyl-5-HT hydrochloride (2-Methyl-5-hydroxytryptamine hydrochloride) (i.p.; 3 mg/kg; 45 minutes) significantly decreases time of immobility as compared to controls thus showing anti-depressive-like effects[1].

Animal Model:Male Sprague-Dawley rats[1]
Dosage:3 mg/kg
Administration:I.p.; 45 minutes
Result:Significantly decreased time of immobility thus showing anti-depressive-like effects.
[IC 50]

5-HT3 Receptor
[storage]

Store at RT
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