| Identification | Back Directory | [Name]
Mitoquinone mesylate | [CAS]
845959-50-4 | [Synonyms]
MitoQ
MitoQ mesylate
MitoQ10 mesylate
Mitoquinol Mesylate
Mitoquinone mesylate
Mitoquinone mesylate, ethanol solution
Mitoquinone mesylate (Mitoquinone methanesulfonate
10-(4,5-dimethoxy-2-methyl-3,6-dioxocyclohexa-1,4-dien-1-yl)decyl-triphenylphosphanium,methanesulfonate | [EINECS(EC#)]
10-1 | [Molecular Formula]
C38H47O7PS | [MDL Number]
MFCD30747833 | [MOL File]
845959-50-4.mol | [Molecular Weight]
678.814 |
| Chemical Properties | Back Directory | [storage temp. ]
-20°C | [solubility ]
Soluble in DMSO. | [form ]
waxy solid | [color ]
Orange | [Stability:]
Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months. | [InChIKey]
GVZFUVXPTPGOQT-UHFFFAOYSA-M | [SMILES]
[P+](CCCCCCCCCCC1C(=O)C(OC)=C(OC)C(=O)C=1C)(C1=CC=CC=C1)(C1=CC=CC=C1)C1=CC=CC=C1.CS([O-])(=O)=O |
| Hazard Information | Back Directory | [Description]
Mitoquinone mesylate (845959-50-4) is a mitochondria-targeted antioxidant.? Displays cardio- and neuroprotective effects.1 Displays beneficial effects in mouse models of Alzheimer’s disease.2,3 Protects pancreatic β-cells against oxidative stress and improves insulin secretion.4 Inhibits respiratory syncytial virus (RSV) production via lowering of mitochondrial ROS levels.5 Cell permeable. | [Uses]
Mitoquinone Mesylate is used in the transport and metabolism of some cationic ubiquinone antioxidants. | [in vivo]
Mitoquinone (MitoQ) treatment significantly reduces pancreatic oedema and neutrophil infiltration. MitoQ dose-dependently increases serum amylase with an approximate doubling at the higher dose. MitoQ treatment nearly doubles lung MPO activity induced by Caerulein with a significant increase of serum IL-6 levels also evident at 10 mg/kg (dose 1)[2]. | [storage]
Store at -20°C | [References]
References/Citations: |
|
|