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7,3′,5′-Trihydroxyflavanone, a flavanoid derivative, induces the apoptotic cell death of MCF-7 cells by increasing Bax expression level. 7,3′,5′-Trihydroxyflavanone also exhibits antioxidant activity[1][2]. | [References]
[1] Abdullah H, et, al. A natural compound from Hydnophytum formicarium induces apoptosis of MCF-7 cells via up-regulation of Bax. Cancer Cell Int. 2010 May 4;10:14. DOI:10.1186/1475-2867-10-14
[2] Tsvetkov DE, et, al. Components of the extracts of the knot wood of Dalbergia Sissoo Linn. and their antioxidant activity. Russian Chemical Bulletin. 2019 Sep; 68:1756-1762. |
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