| Identification | Back Directory | [Name]
Somatostatin-28 (sheep), 8-L-norleucine- (9CI) | [CAS]
84768-30-9 | [Synonyms]
Somatostatin-28 (sheep), 8-L-norleucine- (9CI) | [Molecular Formula]
C138H209N41O39S2 | [MOL File]
84768-30-9.mol | [Molecular Weight]
3130.52 |
| Chemical Properties | Back Directory | [density ]
1.53±0.1 g/cm3(Predicted) | [Sequence]
Ser-Ala-Asn-Ser-Asn-Pro-Ala-{Nle}-Ala-Pro-Arg-Glu-Arg-Lys-Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys (disulfide bridge:Cys17-Cys28) |
| Hazard Information | Back Directory | [Uses]
[Nle8] Somatostatin (1-28) is a derivative of somatosttin (1-28) with norleucine replacing methionine in position 8. [Nle8] Somatostatin (1-28) increases the amylase release.[Nle8] Somatostatin (1-28) increases the cyclic AMP in pancreatic acini [1]. | [References]
[1] Esteve JP, et al. Bimodal regulation of pancreatic exocrine function in vitro by somatostatin-28. Am J Physiol. 1983 Aug;245(2):G208-16. DOI:10.1152/ajpgi.1983.245.2.G208 |
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