ChemicalBook--->CAS DataBase List--->848249-35-4

848249-35-4

848249-35-4 Structure

848249-35-4 Structure
IdentificationBack Directory
[Name]

Acetamide, 2-(2-ethylphenoxy)-N-[2-methyl-4-(1-pyrrolidinyl)phenyl]-
[CAS]

848249-35-4
[Synonyms]

JAMM protein inhibitor 2
2-(2-ethylphenoxy)-N-(2-methyl-4-(pyrrolidin-1-yl)phenyl)acetamide
Acetamide, 2-(2-ethylphenoxy)-N-[2-methyl-4-(1-pyrrolidinyl)phenyl]-
[Molecular Formula]

C21H26N2O2
[MOL File]

848249-35-4.mol
[Molecular Weight]

338.44
Chemical PropertiesBack Directory
[storage temp. ]

4°C, protect from light
[solubility ]

DMSO : 14.71 mg/mL (43.46 mM; ultrasonic and warming and heat to 60°C)
Spectrum DetailBack Directory
[Spectrum Detail]

Acetamide, 2-(2-ethylphenoxy)-N-[2-methyl-4-(1-pyrrolidinyl)phenyl]-(848249-35-4)1HNMR
Hazard InformationBack Directory
[Biological Activity]

JAMM protein inhibitor 2 (compound 180) is a potent JAMM protease inhibitor with IC50s of 10 μM, 46 μM and 89 μM for thrombin, Rpn11 and MMP2, respectively. JAMM protein inhibitor 2 can be used for researching anticancer[1]
[storage]

4°C, protect from light
[References]

[1]. Han-Jie Zhou, et al. Methods and compositions for jamm protease inhibition. WO2013123071A1 (compound 180)
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