| Identification | Back Directory | [Name]
1-Propanone, 1-[4-[[4-[(3-chloro-2-fluorophenyl)amino]-6-hydroxy-7-quinazolinyl]oxy]-1-piperidinyl]-2-hydroxy-, (2S)- | [CAS]
848439-89-4 | [Synonyms]
1-Propanone, 1-[4-[[4-[(3-chloro-2-fluorophenyl)amino]-6-hydroxy-7-quinazolinyl]oxy]-1-piperidinyl]-2-hydroxy-, (2S)- | [Molecular Formula]
C22H22ClFN4O4 | [MOL File]
848439-89-4.mol | [Molecular Weight]
460.89 |
| Hazard Information | Back Directory | [Uses]
AZ5385 is an EGFR-tyrosine kinase inhibitor. AZ5385 is a HRV-2 virus blocker, with EC50 of 0.35 μM. AZ5385 affects the late stage of viral life cycle[1]. | [References]
[1] Miah M, et al. Identification of epidermal growth factor receptor-tyrosine kinase inhibitor targeting the VP1 pocket of human rhinovirus. Antimicrob Agents Chemother. 2024 Mar 6;68(3):e0106423. DOI:10.1128/aac.01064-23 |
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