| Identification | Back Directory | [Name]
2-(1,3-BENZOXAZOL-2-YL)-1-[3-(TRIFLUOROMETHYL)PHENYL]ETHANONE
| [CAS]
849021-37-0 | [Synonyms]
11β-HSD1-IN-10
Ethanone, 2-(2-benzoxazolyl)-1-[3-(trifluoromethyl)phenyl]-
2-(Benzo[d]oxazol-2-yl)-1-(3-(trifluoromethyl)phenyl)ethanone
2-(1,3-Benzoxazol-2-yl)-1-[3-(trifluoromethyl)phenyl]ethan-1-one
2-(1,3-Benzoxazol-2-yl)-1-[3-(trifluoromethyl)phenyl]ethan-1-one 95+%
3-[(1,3-Benzoxazol-2-yl)acetyl]benzotrifluoride, 2-{2-Oxo-2-[3-(trifluoromethyl)phenyl]ethyl}-1,3-benzoxazole | [Molecular Formula]
C16H10F3NO2 | [MDL Number]
MFCD04037916 | [MOL File]
849021-37-0.mol | [Molecular Weight]
305.25 |
| Hazard Information | Back Directory | [Uses]
11β-HSD1-IN-10 (compound c3a) is a potent 11β-HSD1 inhibitor (IC50=1.8 μM for human). 11β-HSD1-IN-10 can be used in studies of obesity, hyperglycemia and cognitive impairment[1]. | [References]
[1] Naredo-Gonzalez G, et al. Non-invasive in vivo assessment of 11β-hydroxysteroid dehydrogenase type 1 activity by 19F-Magnetic Resonance Spectroscopy. Sci Rep. 2022 Sep 29;12(1):16268. DOI:10.1038/s41598-022-18740-5 |
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