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849217-77-2

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849217-77-2 Structure

849217-77-2 Structure
IdentificationBack Directory
[Name]

849217-77-2
[CAS]

849217-77-2
[Synonyms]

849217-77-2
CabozantinibImpurity8HCl
Cabozantinib Metabolite M7
CabozantinibImpurity8SodiumSalt
Cabozantinib Des-O-fluoroaniline
1-((4-((6,7-dimethoxyquinolin-4-yl)oxy)phenyl)carbamoyl)cyclopropane-1-carboxylic acid
Cyclopropanecarboxylic acid,1-[[[4-[(6,7-dimethoxy-4-quinolinyl)oxy]phenyl]amino]carbonyl]-
[Molecular Formula]

C22H20N2O6
[MOL File]

849217-77-2.mol
[Molecular Weight]

408.4
Chemical PropertiesBack Directory
[solubility ]

Acetonitrile (Slightly), Aqueous Acid (Slightly)
[form ]

Solid
[color ]

White to Off-White
Hazard InformationBack Directory
[Uses]

Cabozantinib Des-O-fluoroaniline is a degradation product of Cabozantinib(C051500). Cabozantinib is a small molecule C-Met modulator. Cabozantinib shows dose-dependent inhibition of tumor growth and tumor regression, associated with disruption of the tumor vasculature and extensive tumor cell apoptosis.
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