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849758-44-7

849758-44-7 Structure

849758-44-7 Structure
IdentificationBack Directory
[Name]

Olean-12-en-28-oic acid, 3-[(6-O-β-D-glucopyranosyl-β-D-glucopyranosyl)oxy]-2,16,23-trihydroxy-, O-D-apio-β-D-furanosyl-(1→3)-O-β-D-xylopyranosyl-(1→4)-O-6-deoxy-α-L-mannopyranosyl-(1→2)-α-L-arabinopyranosyl ester, (2β,3β,4α,16α)-
[CAS]

849758-44-7
[Synonyms]

Olean-12-en-28-oic acid, 3-[(6-O-β-D-glucopyranosyl-β-D-glucopyranosyl)oxy]-2,16,23-trihydroxy-, O-D-apio-β-D-furanosyl-(1→3)-O-β-D-xylopyranosyl-(1→4)-O-6-deoxy-α-L-mannopyranosyl-(1→2)-α-L-arabinopyranosyl ester, (2β,3β,4α,16α)-
[Molecular Formula]

C63H102O32
[MOL File]

849758-44-7.mol
[Molecular Weight]

1371.48
Chemical PropertiesBack Directory
[density ]

1.58±0.1 g/cm3(Predicted)
[pka]

12.76±0.70(Predicted)
Hazard InformationBack Directory
[Uses]

Polygalacin D3 is a triterpenoid saponin compound that can be extracted from the roots of the balloon flower. Polygalacin D3 can inhibit the proliferation of non-small cell lung cancer (NSCLC) cell lines by blocking the PI3K/Akt pathway, and it induces cell cycle arrest and cell apoptosis[1].
[Definition]

ChEBI: Polygalacin D3 is a triterpenoid saponin. It has a role as a metabolite.
[References]

[1] Seo YS, et al. Polygalacin D induces apoptosis and cell cycle arrest via the PI3K/Akt pathway in non-small cell lung cancer. Oncol Rep. 2018 Apr;39(4):1702-1710. DOI:10.3892/or.2018.6230
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