| Identification | Back Directory | [Name]
4-(alpha-Methylbenzyl)resorcinol | [CAS]
85-27-8 | [Synonyms]
LGB-PR
Symwhite
BioActive PRL
NanoActive 377
Fat-Soluble 377
Water-Soluble 377
Phenethyl resorcinol
Phenylethyl Resorcinol
-Methylbenzyl)resorcinol
4-(1-Phenylethyl)resorcin
4-(1-Phenylethyl)resorcinol
4-(α-Methylbenzyl)resorcinol
BioActive Phenylethyl Resorcinol
4-(1-phenylethy)-1,3-benzenediol
4-(alpha-Methylbenzyl)resorcinol
4-(1-Phenylethyl)benzene-1,3-diol
Nanoactive Phenylethyl Resorcinol
4-(1-phenylethyl)-1,3-Benzenediol
NanoAcive Phenylethyl Resorcinol
1,3-Benzenediol, 4-(1-phenylethyl)-
4-(alpha-Methylbenzyl)resorcinol>
Nanoactive Phenylethyl Resorcinol (377)
4-(1-Phenylethyl)benzene-1,3-diol,98%,GC
Nanoactive Phenylethyl Resorcinol Symwhite 377 Powder
NanoLiposomal 377, NanoLiposomal Phenethyl Resorcinol | [EINECS(EC#)]
480-070-0 | [Molecular Formula]
C14H14O2 | [MDL Number]
MFCD21648466 | [MOL File]
85-27-8.mol | [Molecular Weight]
214.26 |
| Chemical Properties | Back Directory | [Melting point ]
78-79℃ | [Boiling point ]
244°C/12mmHg(lit.) | [density ]
1.171 | [vapor pressure ]
0Pa at 20℃ | [storage temp. ]
Inert atmosphere,Room Temperature | [solubility ]
Chloroform (Slightly), Ethyl Acetate (Slightly) | [form ]
Solid | [pka]
9.77±0.40(Predicted) | [color ]
Light Beige to Pale Brown | [Water Solubility ]
3.85g/L at 20℃ | [Cosmetics Ingredients Functions]
ANTIOXIDANT | [InChI]
InChI=1S/C14H14O2/c1-10(11-5-3-2-4-6-11)13-8-7-12(15)9-14(13)16/h2-10,15-16H,1H3 | [InChIKey]
PQSXNIMHIHYFEE-UHFFFAOYSA-N | [SMILES]
C1(O)=CC=C(C(C2=CC=CC=C2)C)C(O)=C1 | [LogP]
2.11 at 22℃ |
| Hazard Information | Back Directory | [Uses]
4-(1-Phenylethyl)-1,3-benzenediol is an novel active ingredient of highly efficient skin lightening agents. | [Flammability and Explosibility]
Nonflammable | [Synthesis]
1) Under nitrogen protection, 231 g (2.1 mol) of resorcinol, 4.62 g of the solid acid H2SO4-SiO2, and 220 mL of toluene were added to a reactor, heated to 95 °C, and maintained at that temperature. Subsequently, 104 g (1 mol) of styrene was slowly added dropwise to the reactor at a controlled rate for 1 hour. After completion of the dropwise addition, the reaction was continued at 95 °C for 1 h to obtain the reaction mixture. 2) After completion of the reaction, the reaction mixture was filtered to remove the solid acid H2SO4-SiO2. 150 mL of 0.5% aqueous sodium bicarbonate was added to the filtrate for extraction to separate the organic phase. The organic phase was washed twice more (150 mL each) with deionized water. The organic phase was collected and toluene was removed by rotary evaporator. Subsequently, 250 mL of a mixed solution of hexane and toluene (1:5, v/v) was added for recrystallization, and 177.6 g of white crystal product was obtained in 83% yield. | [References]
[1] Patent: CN105237359, 2016, A. Location in patent: Paragraph 0038; 0039; 0040; 0041; 0042; 0043; 0044
[2] DRP/DRBP Org.Chem.,
[3] Journal of Organic Chemistry, 1952, vol. 17, p. 243,247
[4] Bulletin of the Chemical Society of Japan, 1995, vol. 68, # 10, p. 2955 - 2960
[5] DRP/DRBP Org.Chem., |
|
| Company Name: |
Beri Pharma Co., Ltd. Gold
|
| Telephone: |
0756-8699456 13427714006 |
| Website: |
http://www.zhberi.com |
| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
T&W GROUP
|
| Telephone: |
021-61551611 13296011611 |
| Website: |
www.trustwe.com/ |
|