| Identification | Back Directory | [Name]
N-[2-Acetylthiobenzoyl]-β-alaninamide | [CAS]
850715-59-2 | [Synonyms]
SAMT-247
SAMT-247 >=98% (HPLC)
N-[2-Acetylthiobenzoyl]-β-alaninamide
3-(S-Acetylthiosalicyloyl)aminopropamide
Ethanethioic acid, S-[2-[[(3-amino-3-oxopropyl)amino]carbonyl]phenyl] ester | [Molecular Formula]
C12H14N2O3S | [MOL File]
850715-59-2.mol | [Molecular Weight]
266.32 |
| Chemical Properties | Back Directory | [Melting point ]
168 °C | [Boiling point ]
554.5±35.0 °C(Predicted) | [density ]
1.29±0.1 g/cm3(Predicted) | [storage temp. ]
2-8°C | [solubility ]
H2O: ≥2mg/mL at 60°C | [form ]
powder | [pka]
13.91±0.46(Predicted) | [color ]
white to light yellow | [Water Solubility ]
H2O: ≥2mg/mL at60°C |
| Hazard Information | Back Directory | [Uses]
SAMT-247 may be used in HIV-1 related studies. | [Biological Activity]
SAMT-247 inhibits HIV by modifying the nucleocapsid NCp7 region of Gag in infected cellsblocking Gag processing and reducing infectivity.''SAMT-247 is a microbicide th at decreases the viral infectivity and infectivity of the progeny virus in HIV-1 infections. | [in vivo]
A 1% gel formulation of SAMT-247 protected five of six rhesus macaques from vaginal challenge with a CCR5 (R5) -tropic SHIV[3]. | [IC 50]
HIV-1IIIB: 0.6 μM (EC50) |
|
| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
| Company Name: |
Merck KGaA
|
| Tel: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
|