| Identification | Back Directory | [Name]
Benzonitrile, 4-(4,5-dihydro-1H-imidazol-2-yl)- | [CAS]
850786-33-3 | [Synonyms]
SARS-CoV-2-IN-59
4-(4,5-Dihydro-2-imidazolyl)benzonitrile
4-(4,5-Dihydro-1H-imidazol-2-yl)benzonitrile
Benzonitrile, 4-(4,5-dihydro-1H-imidazol-2-yl)- | [Molecular Formula]
C10H9N3 | [MOL File]
850786-33-3.mol | [Molecular Weight]
171.2 |
| Hazard Information | Back Directory | [Uses]
SARS-CoV-2-IN-59 (compound E07), an imidazoline derivative, is a non-peptide small molecule inhibitor of SARS-CoV-2 that targets the main protease (Mpro) of the coronavirus. SARS-CoV-2-IN-59 has a strong interaction with residues on Mpro (Met 165, Gln 166, Met 165, His 41, Gln 189)[1]. | [References]
[1] Azimi S, et al. Green and rapid and instrumental one-pot method for the synthesis of imidazolines having potential anti-SARS-CoV-2 main protease activity. Sustain Chem Pharm. 2023 Sep;34:101136.. . DOI:10.1016/j.scp.2023.101136 |
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