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851269-75-5

851269-75-5 Structure

851269-75-5 Structure
IdentificationBack Directory
[Name]

N-(2,4-dichlorobenzyl)-1-benzyl-5-oxopyrrolidine-3-carboxamide
[CAS]

851269-75-5
[Synonyms]

P2X7 receptor antagonist-2
N-(2,4-dichlorobenzyl)-1-benzyl-5-oxopyrrolidine-3-carboxamide
3-Pyrrolidinecarboxamide, N-[(2,4-dichlorophenyl)methyl]-5-oxo-1-(phenylmethyl)-
[Molecular Formula]

C19H18Cl2N2O2
[MDL Number]

MFCD06376816
[MOL File]

851269-75-5.mol
[Molecular Weight]

377.26
Chemical PropertiesBack Directory
[form ]

Oil
[color ]

Colorless to light yellow
Hazard InformationBack Directory
[Uses]

P2X7 receptor antagonist-2 is a potent P2X7 receptor antagonist with a pIC50 value of 6.5-7.5. P2X7 receptor antagonist-2 has efficacy of combating neuroinflammation[1].
[References]

[1] Steadman JGA, et, al. 5-oxo-3-pyrrolidinecarboxamide derivatives as p2x7 modulators. WO2009077559A2
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