ChemicalBook--->CAS DataBase List--->851658-10-1

851658-10-1

851658-10-1 Structure

851658-10-1 Structure
IdentificationBack Directory
[Name]

BI Compound D
[CAS]

851658-10-1
[Synonyms]

BI Compound D
4-Amino-8-[3-[(3,4-dimethoxyphenethyl)amino]propyl]-6,6-dimethyl-2-(4-methyl-3-nitrophenyl)-3H-imidazo[4,5-h]isoquinoline-7,9(6H,8H)-dione
[Molecular Formula]

C32H36N6O6
[MOL File]

851658-10-1.mol
[Molecular Weight]

600.66
Chemical PropertiesBack Directory
[Boiling point ]

853.4±75.0 °C(Predicted)
[density ]

1.292±0.06 g/cm3(Predicted)
[form ]

Solid
[pka]

9.93±0.19(Predicted)
[color ]

Light yellow to yellow
Hazard InformationBack Directory
[Description]

OUN58101, also known as MDK-8101, also known as BI-D, is a RSV L-?protein inhibitor. OUN58101 was first reported in patnet WO 2005042530. This product has no formal name at the moment.
[Uses]

RSV L-protein-IN-1 (compound D) is a potent inhibitor of Respiratory syncytial virus (RSV) (EC50=0.021 μM). RSV L-protein-IN-1 inhibits Polymerase (IC50=0.089 μM),and blocks RSV mRNA synthesis by inhibiting guanylation of viral transcripts. RSV L-protein-IN-1 shows moderate cytotoxicity (CC50=8.4 μM,HEp-2),also exhibits activity and lowers virus titers in mouse models of RSV infection[1].
[References]

[1] Liuzzi M, et al. Inhibitors of respiratory syncytial virus replication target cotranscriptional mRNA guanylylation by viral RNA-dependent RNA polymerase. J Virol. 2005 Oct;79(20):13105-15. DOI:10.1128/JVI.79.20.13105-13115.2005
851658-10-1 suppliers list
Company Name: Henan Tianfu Chemical Co.,Ltd.
Tel: +86-0371-55170693 +86-19937530512 , +86-19937530512
Website: https://www.tianfuchem.com/
Company Name: Wuhan Jingkangen Biomedical Technology Co., Ltd  
Tel: 13720134139 086-15871494362 13720134139
Website: https://www.jknbiochem.com
Company Name: Shaoyuan Technology (Shanghai) Co., Ltd.  
Tel: 021-50795510 4000665055
Website: http://www.shao-yuan.com
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Website: https://www.targetmol.cn/
Company Name: Biosynth Biological Technology (Suzhou) Co Ltd  
Tel: 51288865780
Website: www.biosynth.com
Tags:851658-10-1 Related Product Information

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