| Identification | Back Directory | [Name]
MEGA-10 | [CAS]
85261-20-7 | [Synonyms]
MEGA-10
MEGA-10 solution
MEGA-10, ULTROL Grade
MEGA-10 50 mM solution
DECANOYL-N-METHYLGLUCAMIDE
N-Methyl-N-decanoylglucamine
N-DECANOYL-N-METHYLGLUCAMIDE
N-DECANOYL-N-METHYLGLUCAMINE
N-Decanoyl-N-methyl-D-glucamine
N-(D-GLUCITYL)-N-METHYLDECANAMIDE
DECANOYL-N-METHYLGLUCAMIDE (MEGA-10)
DECANOYL-N-METHYLGLUCAMIDE BIOCHEMIKA
N-(D-Gluco-2,3,4,5,6-pentahydroxyhexyl)-N
|N|-Decanoyl-|N|-methylglucamine (MEGA-10)
N-Decanoyl-N-methyl-1-amino-1-deoxy-D-glucitol
D-Glucitol, 1-deoxy-1-methyl(1-oxodecyl)amino-
MEGA-10 (N-DECANOYL-N-METHYLGLUCAMINE) ABOUT 98%
MEGA-10 (N-DECANOYL-N-METHYLGLUCAMINE), 99% MIN., HPLC
N-(D-GLUCO-2,3,4,5,6-PENTAHYDROXYHEXYL)-N-METHYL-DECANAMIDE
Decanoyl-N-MethylglucaMide, N-Decanoyl-N-Methyl-D-glucaMine
N-Methyl-N-((2S,3R,4R,5R)-2,3,4,5,6-pentahydroxyhexyl)decanamide
N-(D-Glucityl)-N-methyldecanamide, N-Decanoyl-N-methyl-D-glucamine, MEGA-10 | [EINECS(EC#)]
617-695-7 | [Molecular Formula]
C17H35NO6 | [MDL Number]
MFCD21607087 | [MOL File]
85261-20-7.mol | [Molecular Weight]
349.46 |
| Chemical Properties | Back Directory | [Melting point ]
91-93 °C | [storage temp. ]
2-8°C | [solubility ]
H2O: 10 mg/mL at 20 °C, clear, colorless | [form ]
Solid | [color ]
White to Off-White | [Water Solubility ]
Soluble in methanol at 50mg/ml. Also soluble in water at 10mg/ml 20 °C | [BRN ]
6974359 | [EPA Substance Registry System]
N-Oxodecyl meglumine (85261-20-7) |
| Hazard Information | Back Directory | [Uses]
Non-ionic detergent for solubilizing membrane proteins | [Purification Methods]
Possible impurities are decanoic acid and N-methylglycamine. The former is removed by grinding the solid with Et2O and then with pet ether and drying over P2O5. It is twice recrystallised from MeOH/Et2O by dissolving in the minimum volume of MeOH, adding Et2O and drying in a vacuum. To remove the glycamine, the solid (800mg) is dissolved in hot H2O (10mL) and set aside. Mega-10 crystallises as colourless needles. These are filtered off and dried in a vacuum to constant weight. It is a good non-ionic non-hygroscopic detergent with a critical micelle concentration (CMC) of 7.4mM (0.26%) in 0.1M Tris-HCl pH 7.4 at 25o. [Hildreth Biochem J 207 363 1982.] |
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