ChemicalBook--->CAS DataBase List--->85261-20-7

85261-20-7

85261-20-7 Structure

85261-20-7 Structure
IdentificationBack Directory
[Name]

MEGA-10
[CAS]

85261-20-7
[Synonyms]

MEGA-10
MEGA-10 solution
MEGA-10, ULTROL Grade
MEGA-10 50 mM solution
DECANOYL-N-METHYLGLUCAMIDE
N-Methyl-N-decanoylglucamine
N-DECANOYL-N-METHYLGLUCAMIDE
N-DECANOYL-N-METHYLGLUCAMINE
N-Decanoyl-N-methyl-D-glucamine
N-(D-GLUCITYL)-N-METHYLDECANAMIDE
DECANOYL-N-METHYLGLUCAMIDE (MEGA-10)
DECANOYL-N-METHYLGLUCAMIDE BIOCHEMIKA
N-(D-Gluco-2,3,4,5,6-pentahydroxyhexyl)-N
|N|-Decanoyl-|N|-methylglucamine (MEGA-10)
N-Decanoyl-N-methyl-1-amino-1-deoxy-D-glucitol
D-Glucitol, 1-deoxy-1-methyl(1-oxodecyl)amino-
MEGA-10 (N-DECANOYL-N-METHYLGLUCAMINE) ABOUT 98%
MEGA-10 (N-DECANOYL-N-METHYLGLUCAMINE), 99% MIN., HPLC
N-(D-GLUCO-2,3,4,5,6-PENTAHYDROXYHEXYL)-N-METHYL-DECANAMIDE
Decanoyl-N-MethylglucaMide, N-Decanoyl-N-Methyl-D-glucaMine
N-Methyl-N-((2S,3R,4R,5R)-2,3,4,5,6-pentahydroxyhexyl)decanamide
N-(D-Glucityl)-N-methyldecanamide, N-Decanoyl-N-methyl-D-glucamine, MEGA-10
[EINECS(EC#)]

617-695-7
[Molecular Formula]

C17H35NO6
[MDL Number]

MFCD21607087
[MOL File]

85261-20-7.mol
[Molecular Weight]

349.46
Chemical PropertiesBack Directory
[Melting point ]

91-93 °C
[Boiling point ]

595.8±50.0 °C(Predicted)
[density ]

1.155±0.06 g/cm3(Predicted)
[storage temp. ]

2-8°C
[solubility ]

H2O: 10 mg/mL at 20 °C, clear, colorless
[form ]

Solid
[pka]

13.44±0.20(Predicted)
[color ]

White to Off-White
[Water Solubility ]

Soluble in methanol at 50mg/ml. Also soluble in water at 10mg/ml 20 °C
[BRN ]

6974359
[EPA Substance Registry System]

N-Oxodecyl meglumine (85261-20-7)
Safety DataBack Directory
[Hazard Codes ]

Xn,Xi
[Risk Statements ]

20/21/22-36/37/38
[Safety Statements ]

22-24/25-37/39-36-26
[WGK Germany ]

3
[F ]

3-9
Hazard InformationBack Directory
[Uses]

Non-ionic detergent for solubilizing membrane proteins
[Purification Methods]

Possible impurities are decanoic acid and N-methylglycamine. The former is removed by grinding the solid with Et2O and then with pet ether and drying over P2O5. It is twice recrystallised from MeOH/Et2O by dissolving in the minimum volume of MeOH, adding Et2O and drying in a vacuum. To remove the glycamine, the solid (800mg) is dissolved in hot H2O (10mL) and set aside. Mega-10 crystallises as colourless needles. These are filtered off and dried in a vacuum to constant weight. It is a good non-ionic non-hygroscopic detergent with a critical micelle concentration (CMC) of 7.4mM (0.26%) in 0.1M Tris-HCl pH 7.4 at 25o. [Hildreth Biochem J 207 363 1982.]
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