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85280-91-7

85280-91-7 Structure

85280-91-7 Structure
IdentificationBack Directory
[Name]

(Z)-7-[(1R)-5α-Hydroxy-2β-[(E,S)-3-hydroxy-5-phenyl-1-pentenyl]-3-oxocyclopentan-1α-yl]-5-heptenoic acid
[CAS]

85280-91-7
[Synonyms]

OAQGPAZDRCBBLD-YTCWWFNZSA-N
17-Phenyl-18,19,20-trinor-PGD2
17-phenyl-18,19,20-trinor-prostaglandin D2
(Z)-7-[(1R)-5α-Hydroxy-2β-[(E,S)-3-hydroxy-5-phenyl-1-pentenyl]-3-oxocyclopentan-1α-yl]-5-heptenoic acid
[Molecular Formula]

C23H30O5
[MOL File]

85280-91-7.mol
[Molecular Weight]

386.48
Chemical PropertiesBack Directory
[solubility ]

DMF: 33 mg/ml; DMSO: 25 mg/ml; Ethanol: miscible; PBS (pH 7.2): 5 mg/ml
Safety DataBack Directory
[Symbol(GHS) ]


GHS02,GHS07,GHS08
[Signal word ]

Danger
Hazard InformationBack Directory
[Description]

17-phenyl trinor Prostaglandin D2 (17-phenyl trinor PGD2) is a novel, chemically stable analog of PGD2 wherein the lower side chain is modified by the addition of a phenyl group at C-17 in place of the last 3 ω-chain carbon atoms. This modification has not been reported in a D-type prostaglandin. However, in the PGE and PGF series, the analogous modification leads to a stable, somewhat more potent agonist which embodies the same biological activities as the parent prostaglandins.
[Uses]

17-phenyl trinor Prostaglandin D2 (17-phenyl trinor PGD2) is a novel, chemically stable analog of PGD2 wherein the lower side chain is modified by the addition of a phenyl group at C-17 in place of the last 3 ω-chain carbon atoms. This modification has not been reported in a D-type prostaglandin. However, in the PGE and PGF series, the analogous modification leads to a stable, somewhat more potent agonist which embodies the same biological activities as the parent prostaglandins.[Cayman Chemical]
[Definition]

ChEBI: A prostanoid that is 18,19,20-trinor-prostaglandin D2 in which one of the terminal methyl hydrogens has been replaced by a phenyl group.
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