| Identification | Back Directory | [Name]
6-Amino-2,5-dihydro-2-(-D-ribofuranosyl)-4H-pyrazolo[3,4-d]pyrimidin-4-one | [CAS]
85426-86-4 | [Synonyms]
6-Amino-2,5-dihydro-2-(-D-ribofuranosyl)-4H-pyrazolo[3,4-d]pyrimidin-4-one
6-Amino-2,5-dihydro-2-(b-D-ribofuranosyl)-4H-pyrazolo[3,4-d]pyrimidin-4-one
4H-Pyrazolo[3,4-d]pyrimidin-4-one, 6-amino-1,2-dihydro-2-β-D-ribofuranosyl-
6-Amino-2,5-dihydro-2-(beta-D-ribofuranosyl)-4H-pyrazolo[3,4-d]pyrimidin-4-one | [Molecular Formula]
C10H13N5O5 | [MOL File]
85426-86-4.mol | [Molecular Weight]
283.241 |
| Hazard Information | Back Directory | [Uses]
6-Amino-1,2-dihydro-2-β-D-ribofuranosyl-4H-pyrazolo[3,4-d]pyrimidin-4-one is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. | [References]
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005 |
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BOC Sciences
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