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85562-55-6

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85562-55-6 Structure

85562-55-6 Structure
IdentificationBack Directory
[Name]

8-CHLORO-2'-DEOXYADENOSINE
[CAS]

85562-55-6
[Synonyms]

8-CL-DADO
8-CHLORO-2'-DEOXYADENOSINE
8-Chloro-2'-deoxy-D-adenosine
Adenosine, 8-chloro-2'-deoxy-
[Molecular Formula]

C10H12ClN5O3
[MDL Number]

MFCD04118032
[MOL File]

85562-55-6.mol
[Molecular Weight]

285.69
Chemical PropertiesBack Directory
[Boiling point ]

660.0±65.0 °C(Predicted)
[density ]

2.03±0.1 g/cm3(Predicted)
[pka]

13.65±0.60(Predicted)
Hazard InformationBack Directory
[Uses]

8-Chloro-2'-deoxyadenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].
[References]

[1] Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500. DOI:10.1016/j.drudis.2021.02.020
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