| Identification | Back Directory | [Name]
2-(2-Azidoacetamido)acetic acid | [CAS]
855750-87-7 | [Synonyms]
N-azidoacetyl-glycine
2-(2-Azidoacetamido)acetic acid
N-(2-azidoacetyl)glycine DCHA salt | [Molecular Formula]
C4H6N4O3 | [MOL File]
855750-87-7.mol | [Molecular Weight]
158.12 |
| Hazard Information | Back Directory | [Uses]
N3-Gly-Gly-OH is a click chemistry reagent. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups. | [References]
[1] Jiang X, et al. Recent applications of click chemistry in drug discovery. Expert Opin Drug Discov. 2019 Aug;14(8):779-789. DOI:10.1080/17460441.2019.1614910 |
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