| Identification | Back Directory | [Name]
3-(piperidin-4-yl)quinolin-2(1h)-one hydrochloride | [CAS]
855778-84-6 | [Synonyms]
3-(piperidin-4-yl)quinolin-2(1h)-one hydrochloride | [Molecular Formula]
C14H17ClN2O | [MOL File]
855778-84-6.mol | [Molecular Weight]
264.75 |
| Chemical Properties | Back Directory | [InChI]
InChI=1S/C14H16N2O.ClH/c17-14-12(10-5-7-15-8-6-10)9-11-3-1-2-4-13(11)16-14;/h1-4,9-10,15H,5-8H2,(H,16,17);1H | [InChIKey]
BAPAUBKDZOEWJL-UHFFFAOYSA-N | [SMILES]
O=C1NC2=CC=CC=C2C=C1C1CCNCC1.Cl |
| Questions And Answer | Back Directory | [Application]
3-(piperidin-4-yl)-1,2-dihydroquinoline-2-one hydrochloride can be used as an important intermediate in the synthesis of new CGRP antagonist compounds. |
| Hazard Information | Back Directory | [Hazard]
3-(piperidin-4-yl)quinolin-2(1h)-one hydrochloride has acute oral toxicity, it causes skin irritation and serious eye irritation.
| [Synthesis]
A stirred solution of tert-butyl 4-(4-hydroxy-2-oxo-1,2,3,4-tetrahydro-quinolin-3-yl)-piperidine-1-carboxylate (5.60 g, 16.2 mmol) in ethyl acetate (70 mL) was treated with HCl/dioxane (4N, 40 mmol, 10 mL). The mixture was stirred at room temperature f |
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| Company Name: |
Energy Chemical
|
| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
| Company Name: |
Shanghai URChem Limited
|
| Telephone: |
+86-021-50890968，021-50891159 +86-18601776121 |
| Website: |
http://www.urchem.com |
|