| Identification | Back Directory | [Name]
2-hydroxyaclacinomycin B | [CAS]
85819-82-5 | [Synonyms]
2-hydroxyaclacinomycin B
1-Naphthacenecarboxylic acid, 4-[[[2''',3''-anhydro]-O-3,6-dideoxy-α-L-erythro-hexopyranos-4-ulos-1-yl-(1→4)-O-2,6-dideoxy-α-L-lyxo-hexopyranosyl-(1→4)-2,3,6-trideoxy-3-(dimethylamino)-α-L-lyxo-hexopyranosyl]oxy]-2-ethyl-1,2,3,4,6,11-hexahydro-2,5,7,9-tetrahydroxy-6,11-dioxo-, methyl ester, [1R-(1α,... | [Molecular Formula]
C42H51NO16 | [MOL File]
85819-82-5.mol | [Molecular Weight]
825.86 |
| Hazard Information | Back Directory | [Uses]
2-Hydroxyaclacinomycin B is an anthracycline antibiotic. 2-Hydroxyaclacinomycin B can be found in Strptomyces galilaeus A-862 (FERM BP-45). 2-Hydroxyaclacinomycin B inhibits RNA synthesis and has anti-tumor activity[1]. | [References]
[1] Yoshimoto A, et al. Anthracycline antibiotic 2-hydroxyaclacinomycins. II. Production of 2-hydroxyaclacinomycins A and B by a new recombinant strain and their antitumor activities. Jpn J Antibiot. 1991 Mar;44(3):277-86. PMID:1880910 |
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