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862073-79-8

862073-79-8 Structure

862073-79-8 Structure
IdentificationBack Directory
[Name]

Salvinorin B Mesylate
[CAS]

862073-79-8
[Synonyms]

Mesyl Sal B
Mesyl Salvinorin B
Mesyl Salvinorin-B
Salvinorin B Mesylate
(2S,?4aR,?6aR,?7R,?9S,?10aS,?10bR)?-2-?(3-?Furanyl)?dodecahydro-?6a,?10b-?dimethyl-?9-?[(methylsulfonyl)?oxy]?-?4,?10-?dioxo-2H-?Naphtho[2,?1-?c]?pyran-?7-?carboxylic Acid Methyl Ester
[Molecular Formula]

C22H28O9S
[MOL File]

862073-79-8.mol
[Molecular Weight]

468.52
Chemical PropertiesBack Directory
[Melting point ]

147-150 °C
[Boiling point ]

649.4±55.0 °C(Predicted)
[density ]

1.37±0.1 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

DMF: 20 mg/ml; DMSO: 20 mg/ml; DMSO:PBS (pH 7.2) (1:7): 0.125 mg/ml; Ethanol: slightly soluble
[form ]

A crystalline solid
Hazard InformationBack Directory
[Uses]

(2S,?4aR,?6aR,?7R,?9S,?10aS,?10bR)?-2-?(3-?Furanyl)?dodecahydro-?6a,?10b-?dimethyl-?9-?[(methylsulfonyl)?oxy]?-?4,?10-?dioxo-2H-?Naphtho[2,?1-?c]?pyran-?7-?carboxylic Acid Methyl Ester is a selective κ-opioid receptor agonist and a related compound of Salvinorin A (S100900).
[in vivo]

Mesyl Salvinorin B (0.3, 1, 3 mg/kg; i.p.; once) prevents the ADE at 3 mg/kg in both male and female mice[1].

Animal Model:8 weeks, Male and female adult C57BL/6J mice[1]
Dosage:0.3, 1, 3 mg/kg
Administration:I.p.; once
Result:Showed less intake than the vehicle-treated ones in the ADE (Alcohol deprivation effect) session at 3 mg/kg.
[storage]

Store at -20°C
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