| Identification | Back Directory | [Name]
3-(3-sulfooxyphenyl)propanoic acid | [CAS]
86321-32-6 | [Synonyms]
3-(3-sulfooxyphenyl)propanoic acid | [Molecular Formula]
C9H10O6S | [MDL Number]
MFCD30550336 | [MOL File]
86321-32-6.mol | [Molecular Weight]
246.24 |
| Chemical Properties | Back Directory | [density ]
1.544±0.06 g/cm3(Predicted) | [storage temp. ]
-20°C | [solubility ]
Methanol: soluble | [form ]
A crystalline solid | [pka]
-3.96±0.18(Predicted) |
| Hazard Information | Back Directory | [Uses]
3-(3-Sulfooxyphenyl)propanoic acid (compound M14) is a metabolite of an anti-dementia agent namely echinacoside. 3-(3-Sulfooxyphenyl)propanoic acid has the potential for the research of neurological and behavioral disorders[1][2]. | [Definition]
ChEBI: 3-(3-sulfooxyphenyl)propanoic acid is a monocarboxylic acid that is propionic acid carrying a 3-sulfooxyphenyl substituent at C-3. It has a role as a metabolite. It is an aryl sulfate and a monocarboxylic acid. It is functionally related to a propionic acid. It is a conjugate acid of a 3-(3-sulfooxyphenyl)propanoic acid anion and a 3-(3-sulfooxyphenyl)propanoate(2-). | [Biological Activity]
3-(3-Hydroxyphenyl)propionic acid (3-HPPA) sulfate is a metabolite of a variety of phenols, including ferulic acid , dihydroferulic acid, and dihydrocaffeic acid , and the glycosides echinacoside and acteoside.1,2 Urinary excretion of 3-HPPA sulfate is reduced in protein-deficient mice infected with C. parvum and increased in mice fed wheat bran or functionalized wheat bran.3 | [References]
1.Ma, Y., Lu, Y., Petrofsky, K., et al.Double-edged metabolic effects from short-term feeding of functionalized wheat bran to mouse revealed by metabolomic profilingJ. Agric. Food Chem69(23)6543-6555(2021)
2.Cui, Q., Pan, Y., Bai, X., et al.Systematic characterization of the metabolites of echinacoside and acteoside from Cistanche tubulosa in rat plasma, bile, urine and feces based on UPLC-ESI-Q-TOF-MSBiomed. Chromatogr.30(9)1406-1415(2015)
3.Bolick, D.T., Mayneris-Perxachs, J., Medlock, G.L., et al.Increased urinary trimethylamine n-oxide following cryptosporidium infection and protein malnutrition independent of microbiome effectsJ. Infect. Dis.216(1)64-71(2017)
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