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863491-70-7

863491-70-7 Structure

863491-70-7 Structure
IdentificationBack Directory
[Name]

PF-02575799
[CAS]

863491-70-7
[Synonyms]

PF-02575799
PF02575799,PF 02575799
6-Quinolinecarboxamide, N-[(1S)-2-[[(4-fluorophenyl)methyl]methylamino]-2-oxo-1-phenylethyl]-2-[[[4'-(1-methylethoxy)[1,1'-biphenyl]-2-yl]carbonyl]amino]-
[Molecular Formula]

C42H37FN4O4
[MDL Number]

MFCD30533363
[MOL File]

863491-70-7.mol
[Molecular Weight]

680.78
Chemical PropertiesBack Directory
[Boiling point ]

854.9±65.0 °C(Predicted)
[density ]

1.263±0.06 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

Soluble in DMSO
[pka]

10.63±0.43(Predicted)
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P305+P351+P338
Hazard InformationBack Directory
[Uses]

PF-02575799, is a microsomal triglyceride transfer protein (MTP) inhibitor with an IC50 of 0.77±0.29 nM.
[in vivo]

PF-02575799 produces appreciable triglyceride effects at its minimally effective dose (10 mg/kg). PF-02575799 significant increase alanine transaminase at 100 mg/kg[1].

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