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864628-19-3

864628-19-3 Structure

864628-19-3 Structure
IdentificationBack Directory
[Name]

5-AMAM-2-CP
[CAS]

864628-19-3
[Synonyms]

5-AMAM-2-CP
Acetamide, N-[(6-chloro-3-pyridinyl)methyl]-N-methyl-
[Molecular Formula]

C9H11ClN2O
[MDL Number]

MFCD29056881
[MOL File]

864628-19-3.mol
[Molecular Weight]

198.65
Chemical PropertiesBack Directory
[Boiling point ]

343.0±32.0 °C(Predicted)
[density ]

1.205±0.06 g/cm3(Predicted)
[pka]

-0.51±0.10(Predicted)
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H319-H302-H335-H315
[Precautionary statements ]

P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P-P264-P270-P301+P312-P330-P501
Hazard InformationBack Directory
[Uses]

5-AMAM-2-CP is a major metabolite of Acetamiprid. Acetamiprid is a neonicotinoid insecticide used worldwide and is a nAChR agonist[1][2].
[in vivo]

5-AMAM-2-CP (5-(N-acetyl-N-methylaminomethyl)-2-chloropyridine) is a hydrolyzed product of Acetamiprid, which can be metabolized to 5-AMAM-2-CP in both blood and urine[1].

[References]

[1] Tadashi Yamamuro, et al. Simultaneous determination of neonicotinoid insecticides in human serum and urine using diatomaceous earth-assisted extraction and liquid chromatography-tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2014 DOI:10.1016/j.jchromb.2014.06.008
[2] Terayama H, et al. Effect of acetamiprid on the immature murine testes. Int J Environ Health Res. 2018 Dec;28(6):683-696. DOI:10.1080/09603123.2018.1504897
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