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866607-35-4

866607-35-4 Structure

866607-35-4 Structure
IdentificationBack Directory
[Name]

D-Glucitol, 1,5-anhydro-1-C-[3-[[5-(4-fluorophenyl)-2-thienyl]Methyl]-4-Methylphenyl]-, tetraacetate, (1S)- (9CI)
[CAS]

866607-35-4
[Synonyms]

Canagliflozin-2
Canagliflozin Tetra
Cagliflozin Impurity 12
D-glucitol tetraacetate
Canagliflozin Impurity 88
canagliflozin impurities8
Tetra Acetyl Canagliflozin
canagliflozin impurities621
(2R,3R,4R,5S,6S)-2-(acetoxymethyl)-6-(3-((5-(4-fluorophenyl)...
(2R,3R,4R,5S,6S)-2-(acetoxyMethyl)-6-(3-((5-(4-fluorophenyl)thiophen-2-yl)Methyl)-4-Methylphenyl)tet
(1S)-1,5-Anhydro-1-C-[3-[[5-(4-fluorophenyl)-2-thienyl]methyl]-4-methylphenyl]-D-glucitol tetraacetate
D-Glucitol,1,5-anhydro-1-C-[3-[[5-(4-fluorophenyl)-2-thienyl]Methyl]-4-Methylphenyl]-, tetraacetate, (1S)
(1S)-1,5-Anhydro-1-C-[3-[[5-(4-fluorophenyl)-2-thienyl]methyl]-4-methylphenyl]-D-glucitol 2,3,4,6-Tetraacetate
(1 S)-1,5-dehydro-1- C-[3-[[5-(4- fluorophenyl)-2-thiophene] methyl ]-4-methylphenyl ]- D- glucol tetraacetate
D-Glucitol, 1,5-anhydro-1-C-[3-[[5-(4-fluorophenyl)-2-thienyl]Methyl]-4-Methylphenyl]-, tetraacetate, (1S)- (9CI)
D-Glucitol, 1,5-anhydro-1-C-[3-[[5-(4-fluorophenyl)-2-thienyl]methyl]-4-methylphenyl]-, 2,3,4,6-tetraacetate, (1S)-
[(2R,3R,4R,5S,6S)-3,4,5-Triacetyloxy-6-[3-[[5-(4-fluorophenyl)thiophen-2-yl]methyl]-4-methylphenyl]oxan-2-yl]methyl acetate
(3(R),4(R),5(S)-triacetoxy-6(S)-{3-[5-(4-fluoro-phenyl)-thiophen-2-ylmethyl]-4-methyl-phenyl}-tetrahydro-pyran-2(R)-yl)methanol acetate
(2R,3R,4R,5S,6S)-2-(acetoxyMethyl)-6-(3-((5-(4-fluorophenyl)thiophen-2-yl)Methyl)-4-Methylphenyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate
Canagliflozin impurity 3/Tetra Acetyl Canagliflozin/(2R,3R,4R,5S,6S)-2-(acetoxymethyl)-6-(3-((5-(4-fluorophenyl) thiophen-2-yl)methyl)-4-methylphenyl)tetrahydro-2H-pyran- 3,4,5-triyl triacetate
Tetra Acetyl CanagliflozinQ: What is Tetra Acetyl Canagliflozin Q: What is the CAS Number of Tetra Acetyl Canagliflozin Q: What is the storage condition of Tetra Acetyl Canagliflozin Q: What are the applications of Tetra Acetyl Canagliflozin
[EINECS(EC#)]

206-141-6
[Molecular Formula]

C32H33FO9S
[MDL Number]

MFCD28167873
[MOL File]

866607-35-4.mol
[Molecular Weight]

612.662
Chemical PropertiesBack Directory
[Melting point ]

160-170 °C
[Boiling point ]

658.3±55.0 °C(Predicted)
[density ]

1.32±0.1 g/cm3(Predicted)
[vapor pressure ]

0Pa at 20℃
[storage temp. ]

Storage temp. 2-8°C
[solubility ]

soluble in Chloroform, Ethyl Acetate, Methanol
[form ]

Solid
[color ]

White
[LogP]

5.5 at 20℃
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P280-P301+P312-P302+P352-P305+P351+P338
[REACH Registrations]

Inactive
Hazard InformationBack Directory
[Uses]

The title compound is an intermediate in the synthesis of Canagliflozin which is a sodium/glucose cotransporter 2 (SGLT2) inhibitor. Canagliflozin has been shown to dose dependently reduce calculated renal threshold for glucose excretion and increase urinary glucose excretion. Canagliflozin is a candidate for the treatment of type 2 diabetes and obesity.
[Flammability and Explosibility]

Notclassified
Spectrum DetailBack Directory
[Spectrum Detail]

D-Glucitol, 1,5-anhydro-1-C-[3-[[5-(4-fluorophenyl)-2-thienyl]Methyl]-4-Methylphenyl]-, tetraacetate, (1S)- (9CI)(866607-35-4)1HNMR
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