| Identification | Back Directory | [Name]
Benzoic acid, 3-[[2-[[9-methyl-2-(4-methylphenyl)-5H-[1]benzopyrano[2,3-d]pyrimidin-4-yl]thio]acetyl]amino]- | [CAS]
866842-71-9 | [Synonyms]
UCK2 Inhibitor-2
Benzoic acid, 3-[[2-[[9-methyl-2-(4-methylphenyl)-5H-[1]benzopyrano[2,3-d]pyrimidin-4-yl]thio]acetyl]amino]- | [Molecular Formula]
C28H23N3O4S | [MOL File]
866842-71-9.mol | [Molecular Weight]
497.56 |
| Hazard Information | Back Directory | [Uses]
UCK2 Inhibitor-2 is a non-competitive uridine-cytidine kinase 2 (UCK2) inhibitor with an IC50 value of 3.8 μM. UCK2 Inhibitor-2 can suppress uridine salvage in cells[1]. | [References]
[1] Ayse Okesli-Armlovich, et al. Discovery of small molecule inhibitors of human uridine-cytidine kinase 2 by high-throughput screening. Bioorg Med Chem Lett. 2019 Sep 15;29(18):2559-2564. DOI:10.1016/j.bmcl.2019.08.010 |
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