| Identification | Back Directory | [Name]
N-[4-[2-[[(3-chlorophenyl)Methyl]aMino]ethyl]phenyl]-2-thiophenecarboxiMidaMide dihydrochloride | [CAS]
866914-87-6 | [Synonyms]
ARL-17477 dihydrochloride hydrate
N-[4-[2-[[(3-chlorophenyl)Methyl]aMino]ethyl]phenyl]-2-thiophenecarboxiMidaMide dihydrochloride
N-[4-[2-[[(3-chlorophenyl)methyl]amino]ethyl]phenyl]-2-thiophenecarboximidamide dihydrochloride hydrate | [Molecular Formula]
C20H22Cl3N3S | [MDL Number]
MFCD21608518 | [MOL File]
866914-87-6.mol | [Molecular Weight]
442.833 |
| Hazard Information | Back Directory | [Uses]
ARL-17477 dihydrochloride hydrate may be used in cell signaling studies. | [Biological Activity]
ARL-17477 is an nNOS specific inhibitor. The IC50 against r at nNOS is 35 nM and it has 100-fold selectivity over endothelial and inducible isoforms. ARL-17477 penetrates the brain, and reduces infarct size and reduces cerebral blood flow in several different rodent models of ischemic brain injury. | [storage]
Desiccate at RT |
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BOC Sciences
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https://www.bocsci.com |
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Merck KGaA
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21-20338288 |
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www.sigmaaldrich.cn |
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