| Identification | Back Directory | [Name]
(S)-Pro-xylane (Synonyms: (S)-Hydroxypropyl tetrahydropyrantriol) | [CAS]
868156-46-1 | [Synonyms]
(S)-Pro-xylane
L-glycero-L-gluco-Octitol, 1,5-anhydro-6,8-dideoxy-
(S)-Pro-xylane (Synonyms: (S)-Hydroxypropyl tetrahydropyrantriol) | [EINECS(EC#)]
456-880-5 | [Molecular Formula]
C8H16O5 | [MOL File]
868156-46-1.mol | [Molecular Weight]
192.21 |
| Chemical Properties | Back Directory | [Boiling point ]
376.0±42.0 °C(Predicted) | [density ]
1.368±0.06 g/cm3(Predicted) | [storage temp. ]
4°C, away from moisture and light | [solubility ]
DMSO: 250 mg/mL (1300.66 mM) | [form ]
Solid | [pka]
13.55±0.70(Predicted) | [color ]
White to off-white | [InChI]
InChI=1/C8H16O5/c1-4(9)2-6-8(12)7(11)5(10)3-13-6/h4-12H,2-3H2,1H3/t4-,5+,6-,7-,8-/s3 | [InChIKey]
KOGFZZYPPGQZFZ-FHYXRTTRNA-N | [SMILES]
C([C@@H]1OC[C@@H](O)[C@H](O)[C@H]1O)[C@@H](O)C |&1:1,4,6,8,10,r| |
| Safety Data | Back Directory | [Symbol(GHS) ]
GHS07 | [Signal word ]
Warning | [Hazard statements ]
H302-H315-H319-H335 | [Precautionary statements ]
P261-P301+P312-P302+P352-P304+P340-P305+P351+P338 | [REACH Registrations]
Active |
| Hazard Information | Back Directory | [Description]
(S)-Pro-xylane is the S-enantiomer of Pro-xylane. Pro-xylane, a biologically active C-glycoside in aqueous media, acts as an activator of glycosaminoglycans (GAGs) biosynthesis. | [Uses]
(S)-Pro-xylane (Hydroxypropyl tetrahydropyrantriol) is a C-glycoside, a
xylose derivative, that stimulates the production of glycosaminoglycans
(GAGs) and heparan sulfate proteoglycans (HSPGs) and induces a higher
deposition of proteins in basement membranes and dermal-epidermal
junctions (DEJs). Pro-xylane is used to maintain skin elasticity and
improve skin aging. | [Synthesis]
In the autoclave, add 461g of intermediate 2,5 liters of isopropanol sequentially, seal the autoclave, replace the nitrogen 3 times, hydrogen displace 1 time, and then dissolve the catalyst [RuCl(cymene)(S-BINAP)] Cl (300mg) in 300mL of isopropanol solution underH2atmosphere, carefully add it to the autoclave, continue to fill hydrogen to 50kgf/cm2, and then heat up to about 60 °C, After stirring the reaction for 6h, stop the reaction, remove the material, and cool down the crystals to obtain βS-type Boseine products.The final product (S)-Pro-xylane can be obtained. |
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