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868844-53-5

868844-53-5 Structure

868844-53-5 Structure
IdentificationBack Directory
[Name]

D-Alanine, D-arginyl-D-tyrosyl-D-threonyl-D-valyl-D-α-glutamyl-D-leucyl-
[CAS]

868844-53-5
[Synonyms]

RYTVELA
d-(RYTVELA)
H-(D)-Arg-(D)-Tyr-(D)-Thr-(D)-Val-(D)-Glu-(D)-Leu-(D)-Ala-OH
D-Alanine, D-arginyl-D-tyrosyl-D-threonyl-D-valyl-D-α-glutamyl-D-leucyl-
[Molecular Formula]

C38H62N10O12
[MOL File]

868844-53-5.mol
[Molecular Weight]

850.97
Chemical PropertiesBack Directory
[density ]

1.42±0.1 g/cm3(Predicted)
[pka]

3.42±0.10(Predicted)
Hazard InformationBack Directory
[Uses]

d-(RYTVELA) is a specific inhibitor of human thymocyte proliferation with an IC50 of 1 nM. d-(RYTVELA) inhibits IL-1–induced signaling pathways[1].
[References]

[1] Tiffany Habelrih, et al. Pharmacodynamic characterization of rytvela, a novel allosteric anti-inflammatory therapeutic, to prevent preterm birth and improve fetal and neonatal outcomes. Am J Obstet Gynecol. 2023, 228, 4. DOI:10.1016/j.ajog.2022.10.007
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